Pathnologic @pathnologic
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Path Geek - All things #pathology
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Herpes Simplex Virus 
Lymphadenitis 
 • Expanded paracortex 
 • HSV-infected cells are 
present in areas
• HSV-infected cells ... HSV #Pathology #Microscopy ... #Clinical #LymphNode
The many faces of the Hodgkin/Reed-Sternberg (HRS) cell: Even as medical students we are aware of
Reed-Sternberg (HRS) cell ... Reed-Sternberg cell ... (RS cell). ... Many variants exist ... ReedSternberg #HRS #cell
Hobnail variant of PTC: micropapillary architecture, dense eosinophilic cytoplasm, hobnail cells with apical nuclei, and marked
Hobnail variant ... cytoplasm, hobnail cells ... PTC #Papillary #Thyroid ... Pathology #Clinical #Microscopy
Here is a lymph node with florid follicular hyperplasia typical of HIV lymphadenitis (so-called "pattern A",
KyleBradleyMD "Pattern ... Warthin-Finkeldey type giant cells ... Monocytoid B cells ... #Pathology #Microscopy ... #LymphNode #Clinical
Diffuse Sclerosis Variant—PTC 
 - Rare variant of PTC 
 - Approximately 3% ofall PTC
Diffuse Sclerosis ... • Carcinoma cells ... around the tumor cells ... PTC #Papillary #Thyroid ... Clinical #Gross #Microscopy
Paracoccidioides brasiliensis Lymphadenitis: 

Paracoccidioidomycosis is a systemic fungal infection rare in the US, but endemic in
fibrosis (A) and well-formed ... seen within giant cells ... Lymphadenitis #Pathology #LymphNode ... #Clinical #Microscopy
Oncocytic Variant of Medullary Carcinoma
Don't assume every oncocytic thyroid tumor is a Hurthle cell neoplasm! Nested
Oncocytic Variant ... every oncocytic thyroid ... tumor is a Hurthle cell ... for oncocytic variant ... Carcinoma #Pathology #Microscopy
Salivary acinic cell carcinoma is usually an H&E diagnosis for me- but this zymogen-granule poor variant
Salivary acinic cell ... zymogen-granule poor variant ... characteristic staining pattern ... Salivary #Acinic #Cell ... Carcinoma #Pathology #Microscopy
A morphologic mosaic of NUT carcinoma: monotonous primitive cells, basophilic to clear cytoplasm, abrupt keratinization, prominent
monotonous primitive cells ... -NUT fusion or variants ... Pathology #Clinical #Microscopy
Signet ring cell histiocytes in lymph node sinuses! This can mimic metastatic adenocarcinoma. Histiocytes have ingested
Signet ring cell ... #SignetRing #Cell ... #Histiocytes #LymphNode ... Pathology #Clinical #Microscopy