Pathnologic @pathnologic
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Here is a lymph node that is lymphoid-depleted, fibrotic, and burned-out, typical of late phase HIV
KyleBradleyMD "Pattern ... infection) - "Pattern ... phase between pattern ... Lymphadenitis #PatternC ... Pathology #Microscopy #LymphNode
Herpes Simplex Virus 
Lymphadenitis 
 • Expanded paracortex 
 • HSV-infected cells are 
present in areas
• HSV-infected cells ... Microscopy #Clinical #LymphNode
Here is a lymph node with florid follicular hyperplasia typical of HIV lymphadenitis (so-called "pattern A",
KyleBradleyMD "Pattern ... Warthin-Finkeldey type giant cells ... Monocytoid B cells ... Lymphadenitis #PatternA ... Pathology #Microscopy #LymphNode
Paracoccidioides brasiliensis Lymphadenitis: 

Paracoccidioidomycosis is a systemic fungal infection rare in the US, but endemic in
fibrosis (A) and well-formed ... seen within giant cells ... Lymphadenitis #Pathology #LymphNode
Salivary acinic cell carcinoma is usually an H&E diagnosis for me- but this zymogen-granule poor variant
Salivary acinic ... cell carcinoma is ... characteristic staining pattern ... LisaRooperMD #Salivary ... #Acinic #Cell #
Signet ring cell histiocytes in lymph node sinuses! This can mimic metastatic adenocarcinoma. Histiocytes have ingested
Signet ring cell ... #SignetRing #Cell ... #Histiocytes #LymphNode
Langerhans cell histiocytosis presenting as a solitary jaw cyst. Classic reniform nuclei, prominent eosinophils, S100+, CD1A+,
Langerhans cell ... presenting as a solitary ... #Langerhans #cell