Pathnologic @pathnologic
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Here is a lymph node that is lymphoid-depleted, fibrotic, and burned-out, typical of late phase HIV
KyleBradleyMD "Pattern ... infection) - "Pattern ... phase between pattern ... #Pathology #Microscopy ... #LymphNode #Clinical
Herpes Simplex Virus 
Lymphadenitis 
 • Expanded paracortex 
 • HSV-infected cells are 
present in areas
• HSV-infected cells ... HSV #Pathology #Microscopy ... #Clinical #LymphNode
Here is a lymph node with florid follicular hyperplasia typical of HIV lymphadenitis (so-called "pattern A",
KyleBradleyMD "Pattern ... Warthin-Finkeldey type giant cells ... Monocytoid B cells ... #Pathology #Microscopy ... #LymphNode #Clinical
Paracoccidioides brasiliensis Lymphadenitis: 

Paracoccidioidomycosis is a systemic fungal infection rare in the US, but endemic in
fibrosis (A) and well-formed ... seen within giant cells ... Lymphadenitis #Pathology #LymphNode ... #Clinical #Microscopy
SMARCB1-deficient sinonasal carcinoma: high grade tumors with varying proportions of basaloid and plasmacytoid/rhabdoid cells; CK+, SMARCB1
deficient sinonasal carcinoma ... plasmacytoid/rhabdoid cells ... deficient #sinonasal #Carcinoma ... #Pathology #Microscopy
Salivary acinic cell carcinoma is usually an H&E diagnosis for me- but this zymogen-granule poor variant
Salivary acinic cell ... carcinoma is usually ... characteristic staining pattern ... Salivary #Acinic #Cell ... #Microscopy #Clinical
Signet ring cell histiocytes in lymph node sinuses! This can mimic metastatic adenocarcinoma. Histiocytes have ingested
Signet ring cell ... #SignetRing #Cell ... #Histiocytes #LymphNode ... Pathology #Clinical #Microscopy
A morphologic mosaic of NUT carcinoma: monotonous primitive cells, basophilic to clear cytoplasm, abrupt keratinization, prominent
mosaic of NUT carcinoma ... monotonous primitive cells ... LisaRooperMD #NUT #carcinoma ... Pathology #Clinical #Microscopy
Squamous-Cell Carcinoma of the Tongue - Intraoral examination revealed a well-circumscribed superficial ulcer, with a homogeneous
Squamous-Cell Carcinoma ... examination revealed a well-circumscribed ... invasive squamous-cell ... carcinoma (Panel ... Tongue #Squamous #Microscopy
Hobnail variant of PTC: micropapillary architecture, dense eosinophilic cytoplasm, hobnail cells with apical nuclei, and marked
cytoplasm, hobnail cells ... Papillary #Thyroid #Carcinoma ... Pathology #Clinical #Microscopy