Pathnologic @pathnologic
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Path Geek - All things #pathology
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Herpes Simplex Virus 
Lymphadenitis 
 • Expanded paracortex 
 • HSV-infected cells are 
present in areas
• HSV-infected cells ... HSV #Pathology #Microscopy ... #Clinical #LymphNode
Here is a lymph node with florid follicular hyperplasia typical of HIV lymphadenitis (so-called "pattern A",
KyleBradleyMD "Pattern ... Warthin-Finkeldey type giant cells ... Monocytoid B cells ... #Pathology #Microscopy ... #LymphNode #Clinical
SMARCB1-deficient sinonasal carcinoma: high grade tumors with varying proportions of basaloid and plasmacytoid/rhabdoid cells; CK+, SMARCB1
deficient sinonasal carcinoma ... plasmacytoid/rhabdoid cells ... synapto; aggressive clinical ... #Pathology #Microscopy ... #Clinical
Hobnail variant of PTC: micropapillary architecture, dense eosinophilic cytoplasm, hobnail cells with apical nuclei, and marked
cytoplasm, hobnail cells ... PTC #Papillary #Thyroid ... #Carcinoma #Pathology ... #Clinical #Microscopy
Paracoccidioides brasiliensis Lymphadenitis: 

Paracoccidioidomycosis is a systemic fungal infection rare in the US, but endemic in
fibrosis (A) and well-formed ... seen within giant cells ... Lymphadenitis #Pathology #LymphNode ... #Clinical #Microscopy
Salivary acinic cell carcinoma is usually an H&E diagnosis for me- but this zymogen-granule poor variant
Salivary acinic cell ... carcinoma is usually ... characteristic staining pattern ... Salivary #Acinic #Cell ... #Microscopy #Clinical
Oncocytic Variant of Medullary Carcinoma
Don't assume every oncocytic thyroid tumor is a Hurthle cell neoplasm! Nested
Variant of Medullary Carcinoma ... every oncocytic thyroid ... tumor is a Hurthle cell ... #Pathology #Microscopy ... #Clinical
Signet ring cell histiocytes in lymph node sinuses! This can mimic metastatic adenocarcinoma. Histiocytes have ingested
Signet ring cell ... #SignetRing #Cell ... #Histiocytes #LymphNode ... #Pathology #Clinical ... #Microscopy
Diffuse Sclerosis Variant—PTC 
 - Rare variant of PTC 
 - Approximately 3% ofall PTC
Cytology: • Carcinoma ... cells arranged ... around the tumor cells ... PTC #Papillary #Thyroid ... #Gross #Microscopy
A morphologic mosaic of NUT carcinoma: monotonous primitive cells, basophilic to clear cytoplasm, abrupt keratinization, prominent
mosaic of NUT carcinoma ... monotonous primitive cells ... LisaRooperMD #NUT #carcinoma ... #Pathology #Clinical ... #Microscopy #Mosaic