Pathnologic @pathnologic
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Path Geek - All things #pathology
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Here is a lymph node that is lymphoid-depleted, fibrotic, and burned-out, typical of late phase HIV
KyleBradleyMD "Pattern ... infection) - "Pattern ... phase between pattern ... #Pathology #Microscopy ... #LymphNode #Clinical
Herpes Simplex Virus 
Lymphadenitis 
 • Expanded paracortex 
 • HSV-infected cells are 
present in areas
• HSV-infected cells ... HSV #Pathology #Microscopy ... #Clinical #LymphNode
Here are the morphological hallmarks of Rhabdomyosarcoma.

 - Broken arrow sign 

 - tad-pole rhabdomyoblasts
rhabdomyoblasts - Wraith cells ... - Cross striations ... Hallmarks #Pathology #Microscopy
Paracoccidioides brasiliensis Lymphadenitis: 

Paracoccidioidomycosis is a systemic fungal infection rare in the US, but endemic in
fibrosis (A) and well-formed ... seen within giant cells ... Lymphadenitis #Pathology #LymphNode ... #Clinical #Microscopy
Here is a lymph node with florid follicular hyperplasia typical of HIV lymphadenitis (so-called "pattern A",
KyleBradleyMD "Pattern ... Warthin-Finkeldey type giant cells ... Monocytoid B cells ... #Pathology #Microscopy ... #LymphNode #Clinical
Signet ring cell histiocytes in lymph node sinuses! This can mimic metastatic adenocarcinoma. Histiocytes have ingested
Signet ring cell ... #SignetRing #Cell ... #Histiocytes #LymphNode ... Pathology #Clinical #Microscopy
Aldosteronoma — Spironolactone Bodies 

1. Spironolactone is often used to treat hypertension caused by hyperaldosteronism, and
Red blood cells ... endoplasmic reticulum in cells ... Pathology #Clinical #Gross ... #Microscopy
Diffuse Sclerosis Variant—PTC 
 - Rare variant of PTC 
 - Approximately 3% ofall PTC
Diffuse Sclerosis ... • Carcinoma cells ... around the tumor cells ... Pathology #Clinical #Gross ... #Microscopy
Salivary acinic cell carcinoma is usually an H&E diagnosis for me- but this zymogen-granule poor variant
Salivary acinic cell ... characteristic staining pattern ... Salivary #Acinic #Cell ... Carcinoma #Pathology #Microscopy