Pathnologic @pathnologic
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Here is a lymph node that is lymphoid-depleted, fibrotic, and burned-out, typical of late phase HIV
KyleBradleyMD "Pattern ... infection) - "Pattern ... phase between pattern ... #Pathology #Microscopy ... #LymphNode #Clinical
Herpes Simplex Virus 
Lymphadenitis 
 • Expanded paracortex 
 • HSV-infected cells are 
present in areas
• HSV-infected cells ... Lymphadenitis #HSV #Pathology ... Microscopy #Clinical #LymphNode
Here are the morphological hallmarks of Rhabdomyosarcoma.

 - Broken arrow sign 

 - tad-pole rhabdomyoblasts
rhabdomyoblasts - Wraith cells ... - Cross striations ... Rhabdomyosarcoma #Hallmarks #Pathology
Here is a lymph node with florid follicular hyperplasia typical of HIV lymphadenitis (so-called "pattern A",
KyleBradleyMD "Pattern ... Warthin-Finkeldey type giant cells ... Monocytoid B cells ... #Pathology #Microscopy ... #LymphNode #Clinical
Paracoccidioides brasiliensis Lymphadenitis: 

Paracoccidioidomycosis is a systemic fungal infection rare in the US, but endemic in
fibrosis (A) and well-formed ... seen within giant cells ... Lymphadenitis #Pathology ... #LymphNode #Clinical
Signet ring cell histiocytes in lymph node sinuses! This can mimic metastatic adenocarcinoma. Histiocytes have ingested
Signet ring cell ... #SignetRing #Cell ... #Histiocytes #LymphNode ... #Pathology #Clinical
Aldosteronoma — Spironolactone Bodies 

1. Spironolactone is often used to treat hypertension caused by hyperaldosteronism, and
Red blood cells ... endoplasmic reticulum in cells ... Spironolactone #Bodies #Pathology ... #Clinical #Gross
Diffuse Sclerosis Variant—PTC 
 - Rare variant of PTC 
 - Approximately 3% ofall PTC
Diffuse Sclerosis ... • Carcinoma cells ... around the tumor cells ... Thyroid #Cancer #Pathology ... #Clinical #Gross
Salivary acinic cell carcinoma is usually an H&E diagnosis for me- but this zymogen-granule poor variant
Salivary acinic cell ... characteristic staining pattern ... Salivary #Acinic #Cell ... #Carcinoma #Pathology
LAMP2 cardiomyopathy in a 12-year-old boy with sudden death (Table 1; patient #1). A. At autopsy,
cardiac muscle cells ... , or groups of cells ... #Clinical #Gross ... #Pathology #HOCM