Pathnologic @pathnologic
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Herpes Simplex Virus 
Lymphadenitis 
 • Expanded paracortex 
 • HSV-infected cells are 
present in areas
Herpes Simplex Virus ... • HSV-infected cells ... #Simplex #Virus ... Lymphadenitis #HSV #Pathology ... Microscopy #Clinical #LymphNode
Here is a lymph node that is lymphoid-depleted, fibrotic, and burned-out, typical of late phase HIV
Here is a lymph ... KyleBradleyMD "Pattern ... infection) - "Pattern ... #Pathology #Microscopy ... #LymphNode #Clinical
Here is a lymph node with florid follicular hyperplasia typical of HIV lymphadenitis (so-called "pattern A",
Here is a lymph ... Warthin-Finkeldey type giant cells ... Monocytoid B cells ... #Pathology #Microscopy ... #LymphNode #Clinical
Paracoccidioides brasiliensis Lymphadenitis: 

Paracoccidioidomycosis is a systemic fungal infection rare in the US, but endemic in
fibrosis (A) and well-formed ... seen within giant cells ... Lymphadenitis #Pathology ... #LymphNode #Clinical
Here are the morphological hallmarks of Rhabdomyosarcoma.

 - Broken arrow sign 

 - tad-pole rhabdomyoblasts
Here are the morphological ... rhabdomyoblasts - Wraith cells ... Rhabdomyosarcoma #Hallmarks #Pathology
Signet ring cell histiocytes in lymph node sinuses! This can mimic metastatic adenocarcinoma. Histiocytes have ingested
Signet ring cell ... #SignetRing #Cell ... #Histiocytes #LymphNode ... #Pathology #Clinical
Acute Graft versus Host disease: vacuolar interface dermatitis w/ lymphoexocytosis, dyskeratotic keratinocytes, notable satellite cell necrosis.
notable satellite cell ... after BMT like here ... Host #disease #Pathology
Olfactory Neuroblastoma Pathology

Morphology and other IHC clinched the diagnosis of olfactory neuroblastoma here. The tumor had
Neuroblastoma Pathology ... neuroblastoma here ... sustentacular cells ... Neuroblastoma #Pathology
Salivary acinic cell carcinoma is usually an H&E diagnosis for me- but this zymogen-granule poor variant
Salivary acinic cell ... characteristic staining pattern ... Salivary #Acinic #Cell ... #Carcinoma #Pathology
Myeloma: In this BM core, most plasma cells contain cytoplasmic immunoglobulin (Russell bodies).

They're difficult to identify
core, most plasma cells ... identify as plasma cells ... CD138 helps (same ... BoneMarrow #Clinical #Pathology