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Sickle cell anemia and Howell Jolly bodies (nuclear remnants).

 - Dr. Abubaker Elshaikh
@ElshaikhMD

#SickleCell #HowellJolly #Body #Bodies
Sickle cell anemia ... and Howell Jolly bodies ... HowellJolly #Body #Bodies ... Smear #Clinical #Microscopy
Paracoccidioides brasiliensis Lymphadenitis: 

Paracoccidioidomycosis is a systemic fungal infection rare in the US, but endemic in
Head&neck, Lymph Nodes ... fibrosis (A) and well-formed ... seen within giant cells ... Lymphadenitis #Pathology #LymphNode ... #Clinical #Microscopy
Herpes Simplex Virus 
Lymphadenitis 
 • Expanded paracortex 
 • HSV-infected cells are 
present in areas
• HSV-infected cells ... HSV #Pathology #Microscopy ... #Clinical #LymphNode
Here is a lymph node that is lymphoid-depleted, fibrotic, and burned-out, typical of late phase HIV
seen in lymph nodes ... PatternC #Pathology #Microscopy ... #LymphNode #Clinical
Aldosteronoma — Spironolactone Bodies 

1. Spironolactone is often used to treat hypertension caused by hyperaldosteronism, and
Spironolactone Bodies ... Red blood cells ... spironolactone bodies ... endoplasmic reticulum in cells ... Clinical #Gross #Microscopy
Signet ring cell histiocytes in lymph node sinuses! This can mimic metastatic adenocarcinoma. Histiocytes have ingested
Signet ring cell ... #SignetRing #Cell ... #Histiocytes #LymphNode ... Pathology #Clinical #Microscopy
On the left radiological pathological correlation of Langerhans cell histiocytosis in respectively nodular stage and early
of Langerhans cell ... #Clinical #Radiology ... #Pathology #CTChest ... #Microscopy #LCH
Neoplastic plasma cells with nucleoli (left image) and intranuclear Dutcher body (right image).

Dutcher bodies are round,
Neoplastic plasma cells ... Dutcher bodies are ... #DutcherBody #Bodies ... Clinical #Smear #Microscopy
Here is a lymph node with florid follicular hyperplasia typical of HIV lymphadenitis (so-called "pattern A",
Warthin-Finkeldey type giant cells ... Monocytoid B cells ... PatternA #Pathology #Microscopy ... #LymphNode #Clinical
Diffuse Sclerosis Variant—PTC 
 - Rare variant of PTC 
 - Approximately 3% ofall PTC
• Carcinoma cells ... Numerous psammoma bodies ... around the tumor cells ... Clinical #Gross #Microscopy