Pathnologic @pathnologic
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Sickle cell anemia and Howell Jolly bodies (nuclear remnants).

 - Dr. Abubaker Elshaikh
@ElshaikhMD

#SickleCell #HowellJolly #Body #Bodies
Sickle cell anemia ... #HowellJolly #Body ... Hematology #Smear #Clinical
Codocytes (Target cells) - Two target cells are seen in the left photo and one in
Codocytes (Target cells ... ) - Two target cells ... a Howell-Jolly body ... Target cells are ... #Clinical #Path
Amiodarone induced thyroid changes

Histopath: Remarkably enlarged follicles, distended with colloid, without 
scalloping, and lined by flattened
Amiodarone induced thyroid ... flattened follicular cells ... change, Follicular cells ... #Amiodarone #thyroid ... AIT #Pathology #Clinical
A – cabot ring, B – Howell-Jolly Body

What are Cabot’s rings?
- They are delicate threadlike inclusions
– Howell-Jolly Body ... the red blood cells ... #Clinical #Pathology
Hobnail variant of PTC: micropapillary architecture, dense eosinophilic cytoplasm, hobnail cells with apical nuclei, and marked
cytoplasm, hobnail cells ... PTC #Papillary #Thyroid ... Carcinoma #Pathology #Clinical
Aldosteronoma — Spironolactone Bodies 

1. Spironolactone is often used to treat hypertension caused by hyperaldosteronism, and
spironolactone body ... Red blood cells ... endoplasmic reticulum in cells ... Bodies #Pathology #Clinical
Oncocytic Variant of Medullary Carcinoma
Don't assume every oncocytic thyroid tumor is a Hurthle cell neoplasm! Nested
every oncocytic thyroid ... tumor is a Hurthle cell ... here should raise concern ... Pathology #Microscopy #Clinical
Howell-Jolly Body - On these Wright-stained peripheral blood smears the small dark spheres within red cells
Howell-Jolly Body ... spheres within red cells ... more than one H-J body ... within a red cell ... #Clinical #Path
Diffuse Sclerosis Variant—PTC 
 - Rare variant of PTC 
 - Approximately 3% ofall PTC
• Carcinoma cells ... around the tumor cells ... PTC #Papillary #Thyroid ... #Cancer #Pathology ... #Clinical #Gross
Myeloma: In this BM core, most plasma cells contain cytoplasmic immunoglobulin (Russell bodies).

They're difficult to identify
core, most plasma cells ... identify as plasma cells ... RussellBodies #Body ... PlasmaCells #BoneMarrow #Clinical