Pathnologic @pathnologic
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Pathology - Castleman disease. 

Mediastinal mass in a younger woman.

Histologic Features of Castleman disease, hyaline vascular
blood vessels - Germinal ... center 'twinning ... - Hyalinized germinal ... Pathology #Smear #Microscopy ... #Clinical
Herpes Simplex Virus 
Lymphadenitis 
 • Expanded paracortex 
 • HSV-infected cells are 
present in areas
HSV #Pathology #Microscopy ... #Clinical #LymphNode
Focus of Metastatic Melanoma Colonizing a Germinal Center

I thought these big cells were funny immunoblasts- until
Melanoma Colonizing a Germinal ... Center I thought ... melanoma colonizing a germinal ... Metastatic #melanoma #germinal ... #Clinical #Microscopy
Here is a lymph node that is lymphoid-depleted, fibrotic, and burned-out, typical of late phase HIV
PatternC #Pathology #Microscopy ... #LymphNode #Clinical
Paracoccidioides brasiliensis Lymphadenitis: 

Paracoccidioidomycosis is a systemic fungal infection rare in the US, but endemic in
Lymphadenitis #Pathology #LymphNode ... #Clinical #Microscopy
Here is a lymph node with florid follicular hyperplasia typical of HIV lymphadenitis (so-called "pattern A",
proliferative germinal ... PatternA #Pathology #Microscopy ... #LymphNode #Clinical
Amiodarone induced thyroid changes

Histopath: Remarkably enlarged follicles, distended with colloid, without 
scalloping, and lined by flattened
Amiodarone induced thyroid ... #Amiodarone #thyroid ... AIT #Pathology #Clinical ... #Microscopy
Hobnail variant of PTC: micropapillary architecture, dense eosinophilic cytoplasm, hobnail cells with apical nuclei, and marked
PTC #Papillary #Thyroid ... Carcinoma #Pathology #Clinical ... #Microscopy
Signet ring cell histiocytes in lymph node sinuses! This can mimic metastatic adenocarcinoma. Histiocytes have ingested
#Histiocytes #LymphNode ... #Pathology #Clinical ... #Microscopy
Oncocytic Variant of Medullary Carcinoma
Don't assume every oncocytic thyroid tumor is a Hurthle cell neoplasm! Nested
every oncocytic thyroid ... here should raise concern ... Carcinoma #Pathology #Microscopy ... #Clinical