Pathnologic @pathnologic
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Path Geek - All things #pathology
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Herpes Simplex Virus 
Lymphadenitis 
 • Expanded paracortex 
 • HSV-infected cells are 
present in areas
Herpes Simplex Virus ... • HSV-infected cells ... DennisOMalleyMD) #Herpes ... HSV #Pathology #Microscopy ... #Clinical #LymphNode
Paracoccidioides brasiliensis Lymphadenitis: 

Paracoccidioidomycosis is a systemic fungal infection rare in the US, but endemic in
fibrosis (A) and well-formed ... seen within giant cells ... Lymphadenitis #Pathology #LymphNode ... #Clinical #Microscopy
Here are the morphological hallmarks of Rhabdomyosarcoma.

 - Broken arrow sign 

 - tad-pole rhabdomyoblasts
Here are the morphological ... rhabdomyoblasts - Wraith cells ... Hallmarks #Pathology #Microscopy
Here is a lymph node that is lymphoid-depleted, fibrotic, and burned-out, typical of late phase HIV
Here is a lymph ... PatternC #Pathology #Microscopy ... #LymphNode #Clinical
Acute Graft versus Host disease: vacuolar interface dermatitis w/ lymphoexocytosis, dyskeratotic keratinocytes, notable satellite cell necrosis.
notable satellite cell ... after BMT like here ... disease #Pathology #Microscopy
Amiodarone induced thyroid changes

Histopath: Remarkably enlarged follicles, distended with colloid, without 
scalloping, and lined by flattened
Amiodarone induced thyroid ... flattened follicular cells ... change, Follicular cells ... #Amiodarone #thyroid ... Pathology #Clinical #Microscopy
Signet ring cell histiocytes in lymph node sinuses! This can mimic metastatic adenocarcinoma. Histiocytes have ingested
Signet ring cell ... #SignetRing #Cell ... #Histiocytes #LymphNode ... Pathology #Clinical #Microscopy
Hobnail variant of PTC: micropapillary architecture, dense eosinophilic cytoplasm, hobnail cells with apical nuclei, and marked
cytoplasm, hobnail cells ... PTC #Papillary #Thyroid ... Pathology #Clinical #Microscopy
Here is a lymph node with florid follicular hyperplasia typical of HIV lymphadenitis (so-called "pattern A",
Here is a lymph ... Warthin-Finkeldey type giant cells ... Monocytoid B cells ... PatternA #Pathology #Microscopy ... #LymphNode #Clinical
Oncocytic Variant of Medullary Carcinoma
Don't assume every oncocytic thyroid tumor is a Hurthle cell neoplasm! Nested
every oncocytic thyroid ... tumor is a Hurthle cell ... amyloid as seen here ... Carcinoma #Pathology #Microscopy