Pathnologic @pathnologic
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Here is a lymph node that is lymphoid-depleted, fibrotic, and burned-out, typical of late phase HIV
of late phase HIV ... C" in HIV Lymphadenitis ... with late phase HIV ... #PatternC #Pathology ... #Microscopy #LymphNode
Herpes Simplex Virus 
Lymphadenitis 
 • Expanded paracortex 
 • HSV-infected cells are 
present in areas
paracortex • HSV-infected ... cells are present ... Lymphadenitis #HSV ... #Pathology #Microscopy ... #Clinical #LymphNode
Here is a lymph node with florid follicular hyperplasia typical of HIV lymphadenitis (so-called "pattern A",
KyleBradleyMD "Pattern ... Warthin-Finkeldey type giant cells ... Monocytoid B cells ... #Pathology #Microscopy ... #LymphNode #Clinical
Hobnail variant of PTC: micropapillary architecture, dense eosinophilic cytoplasm, hobnail cells with apical nuclei, and marked
Hobnail variant ... cytoplasm, hobnail cells ... PTC #Papillary #Thyroid ... #Carcinoma #Pathology ... #Clinical #Microscopy
Oncocytic Variant of Medullary Carcinoma
Don't assume every oncocytic thyroid tumor is a Hurthle cell neoplasm! Nested
Oncocytic Variant ... every oncocytic thyroid ... tumor is a Hurthle cell ... Medullary #Carcinoma #Pathology ... #Microscopy #Clinical
Diffuse Sclerosis Variant—PTC 
 - Rare variant of PTC 
 - Approximately 3% ofall PTC
Diffuse Sclerosis ... • Carcinoma cells ... PTC #Papillary #Thyroid ... #Cancer #Pathology ... Clinical #Gross #Microscopy
Salivary acinic cell carcinoma is usually an H&E diagnosis for me- but this zymogen-granule poor variant
Salivary acinic cell ... zymogen-granule poor variant ... characteristic staining pattern ... #Carcinoma #Pathology ... #Microscopy #Clinical