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diagnosis nephrology differential injury kidney kidneyinjury urine workup acutekidneyinjury ain ana antibodies antibody antineutrophil antinuclear bloodsmear borrelia clinical clinicopathology crystals
Algorithmic Approach to Acute Interstitial Nephritis When to suspect AIN? (not sensitive) • AKI, AKD, rapidly progressive
Algorithmic Approach ... sensitive) • AKI ... sterile pyuria, WBC casts ... eosinophiluria, microscopic ... proteinuria, granular casts
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... - AKI Workup Algorithm ... dipstick, urine microscopy ... osmolarity If cause ... Glomerulonephritis / Vasculits: ANCA
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm Acute Kidney Injury (AKI) - Acute increase
Causes of Acute ... (AKI) - Acute increase ... • Hepatorenal syndromes ... Epithelial cell casts ... polyangiitis /microscopic
Urine Microscopy - Casts Acellular Casts • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... suggestive of acute ... in a variety of acute ... suggestive of nephrotic sydnrome ... #Urine #Microscopy
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Anti-dsDNA (in 70% of cases ... seen in 30—70% of cases ... • Sjögren syndrome ... - Anti-U1-RNP ANCA-Associated ... Vasculitis: • Microscopic
Simplified Approach to Acute Kidney Injury (AKI) 1) IS THIS AN EMERGENCY? Is there a dialysis indication
Simplified Approach to Acute ... cases are caused ... Assess UA w/ microscopy ... for WBCs, RBCs, casts ... #Acute #KidneyInjury
Acute Kidney Injury (AKI) - Differential Diagnosis Framework Pre-Renal: • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Acute Kidney Injury ... Abdominal Compartment Syndrome ... Vasculitis • GN: ANCA ... Diagnosis #nephrology #causes ... #algorithm
Guide to Acute Kidney Injury (AKI) What to ask/look for: - HPI, PMH, full ROS
Guide to Acute Kidney ... - Urinalysis/microscopy ... rhabdo/TLS) Causes ... Nephrology #Diagnosis #Algorithm ... #Causes #Differential
Urinary Casts and Disease Associations Hyaline - May be nonspecific; seen in normal individuals or during severe
Urinary Casts and ... breakdown of cellular casts ... heme-granular casts ... 34t5DgJ #Urinary #Casts ... #Differential #Microscopy
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Differential Diagnosis Algorithm ... • Fanconi's syndrome ... sediment - WBC/RBC casts ... polyangiitis (GPA) / microscopic ... #Causes
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