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HepatoRenal Syndrome - Pathophysiology

Dr. Edgar V. Lerma @edgarvlermamd - Nephrology Secrets https://amzn.to/34t5DgJ

#HRS #HepatoRenal #Syndrome #Pathophysiology #Diagnosis
HepatoRenal Syndrome ... - Pathophysiology ... #Syndrome #Pathophysiology ... #Diagnosis #Nephrology ... #AKI
Hepatorenal Syndrome (HRS) - Diagnostic Criteria
HRS-AKI (Acute: previously known as HRS Type 1)
 • ↑ Creatinine
Hepatorenal Syndrome ... (HRS) - Diagnostic ... Criteria HRS-AKI ... (Acute: previously ... #Syndrome #diagnosis
Acute Kidney Injury - RIFLE and AKIN Criteria for Diagnosis and Classification of AKI
 • AKIN
Acute Kidney Injury ... Criteria for Diagnosis ... mg/dL with an acute ... #RIFLE #AKIN #Criteria ... #Diagnosis #Classification
Acute Kidney Injury - Classification
Prerenal:
 • Dehydration
 • Heart failure (a.k.a. cardiorenal syndrome)
 • Liver failure
a.k.a. cardiorenal syndrome ... failure (a.k.a. hepatorenal ... syndrome) Intrarenal ... prolonged prerenal AKI ... Classification #diagnosis
Clinical manifestations of acute liver failure 

Brain: 
Hepatic encephalopathy,  
Cerebral edema,  
Intracranial hypertension,
manifestations of acute ... and adrenals: Hepatorenal ... syndrome, Hepatoadrenal ... lung injury, Acute ... Signs #Symptoms #Diagnosis
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm
Acute Kidney Injury (AKI) - Acute increase
Kidney Injury (AKI ... - Differential Diagnosis ... Hypoperfusion • Hepatorenal ... syndromes • Drugs ... #Differential #Diagnosis
Common causes of Acute Kidney Injury AKI - Differential Diagnosis
HEMODYNAMIC
 • Cardiac failure: Impaired forward flow,
Kidney Injury AKI ... - Differential Diagnosis ... calcineurin inhibitors, hepatorenal ... syndrome) • Vascular ... #Differential #Diagnosis
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
Hepatorenal Syndrome ... hepatitis, or acute ... Pathophysiology: ... Criteria): • ↑ ... #HRS #Hepatorenal
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Prerenal:
 • Due to true volume loss or decreased
(AKI) - Differential ... Diagnosis Framework ... : cardiorenal, hepatorenal ... Kidney #Injury #AKI ... #Differential #Diagnosis
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
Acute Kidney Injury ... (AKI) in Patients ... cyclophosphamide) #Acute ... Kidney #Injury #AKI ... #Differential #Diagnosis