40 results
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
- Differential Diagnosis ... Polycythemia Vera • Chronic ... Infectious: • Acute ... or Chronic Inflammatory ... effect following treatment
Approach to Gout
Diagnosis: r/o septic arthritis! Needle-shaped, negative birefringent crystals
Treatment:
 • Weight loss, diet, d/c culprit
Approach to Gout Diagnosis ... medications • Acute ... and chronic treatment ... Pegloticase When to start ... #ULT #rheumatology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
- Differential Diagnosis ... Blood Loss • Acute ... RBCs on Smear • Chronic ... • Anemia of Chronic ... Algorithm #Causes #Hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
Diagnostic Framework ... • Anemia of chronic ... kidney disease, Acute ... #differential #diagnosis ... #causes #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... → Refer to hematology ... Rebound effect from treatment ... • Infections: Chronic ... #Differential #Diagnosis
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Syndrome (MD) - Diagnosis ... transformation to acute ... only curative treatment ... #Management #treatment ... #hematology #oncology
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
> 20x normal - Acute ... 5-10x normal - Chronic ... By AST:ALT Ratio ... Liver #Injury #hepatology ... #differential #diagnosis
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
- Differential Diagnosis ... Thrombocytosis): • Acute ... hemorrhage) • Chronic ... myeloid leukemia (CML ... #Causes #hematology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
- Differential Diagnosis ... Fatigue • Acute ... Age > 50 • Chronic ... Algorithm #Causes #Hematology ... #Oncology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... #Chronic #Liver ... Failure #Cirrhosis #Hepatology ... gastroenterology #management #diagnosis