20 results
Primary and Secondary Causes of Mitral Regurgitation
Primary (organic) chronic mitral regurgitation:
 • Leaflet: Rheumatic fever, Infective
and Secondary Causes ... annulus valve: ... cardiomyopathy - VA Joint ... Regurgitation #differential ... #diagnosis #cardiology
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
) Inflammatory joint ... pain (especially ... the face (many differential ... 9) Unexplained fever ... #clues #system
Infectious Joint Pain - Differential Diagnosis Algorithm 
Polyarticular Join Pain
 • Viral Myalgia
 • Viral Arthritis
Infectious Joint ... Pain - Differential ... PainViral ... Infection • Endocarditis ... #Orthopedics #Causes
Inflammatory Joint Pain - Differential Diagnosis Algorithm 
Monoarticular
 • Gout (Podagra, Tophi)
 • Pseudogout
 • Early
Pain - Differential ... Diagnosis Algorithm ... • Rheumatic Fever ... Arthritis • Systemic Lupus ... #Orthopedics #Causes
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
(SLE) General: Fever ... Pericarditis, Endocarditis ... , Aortic valve lesions ... Abdominal pain ... signs #symptoms #diagnosis
Myositis and Myopathies
Polymyositis 
 • Progressive, symmetric muscle weakness 
 • Elevated CK, +Anti-Jo, +Anti-Mi2
Dermatomyositis
Rheumatica • Pain ... , Fever, No muscle ... Detectable HIV viral ... Myopathies #myopathy #differential ... #diagnosis #comparison
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Pain - Diagnostic ... acute rheumatic fever ... spondyloarthropathies, lupus ... #Joint #Pain #MSK ... approach #workup #differential
Causes of Severe Aortic Regurgitation - Differential Diagnosis
Acute:
 • Leaflet: Traumatic Rupture, Acute Infective Endocarditis, Acute
Causes of Severe ... Diagnosis Acute ... , Rheumatic Fever ... Inflammatory: Lupus ... #Diagnosis #Causes
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Pain Eyes ... Subacute bacterial endocarditis ... - Bacterial endocarditis ... #pain #differential ... #diagnosis #rheumatology
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
Involves aortic and mitral ... night sweats, fever ... Marantic (NTBE) Differential ... Persistent bacteremia/fevers ... #Endocarditis #diagnosis