2564 results
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
screening test Anti-dsDNA ... block • Sjogren syndrome ... polymyositis overlap syndrome ... ) Anti-Smith - ... severe disease Treatment
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
papules 30% w/ anti-synthetase ... syndrome- Classic ... Around half of anti-SRP ... and anti-HMGCR ... after 2 years of treatment
Hepatorenal Syndrome - Diagnosis and Management Summary
Who gets HRS?
 • Decompensated cirrhosis
 • Typically with existing
Hepatorenal Syndrome ... infection Mainstay of treatment ... output • Proposed anti-oxidant ... , anti-inflammatory ... #Hepatorenal #Syndrome
Hantavirus
Pathogen: Hantavirus - Rodents are the primary reservoir
Transmission:
 • Shed in the urine, feces, saliva of
Cardiopulmonary Syndrome ... • Specific anti-hantavirus ... • Autopsy PCR Treatment ... diagnosis #management #treatment
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
disorders • Testing anti-GAD ... : • Anti-GAD Ab ... Treatment: • ... IVIG: Rituximab (anti-CD20 ... Diagnosis #Management #treatment
PCOS Treatment
1st line = weight loss
 • 5-10% weight loss can restore ovulatory cycles
 • Improvement
PCOS Treatment ... protection or anti-androgen ... waxing #PCOS #Treatment ... Polycystic #ovary #syndrome
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Pulmonary Renal Syndromes ... polyangiitis) Anti-basement ... Pulmonary Renal Syndromes ... ANCA antibody, Anti-GBM ... diagnosis #management #treatment
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... SLE • Mikulicz syndrome ... • Antibodies: Anti-Ro ... /SSA & Anti-La/SSB ... Adenocarcinoma Treatment
Antiphospholipid Syndrome (APS)
APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
Antiphospholipid Syndrome ... antibodies (aCL) • Anti-ß2 ... to be present Treatment ... Antiphospholipid #Syndrome
Staphylococcal Scalded Skin Syndrome (SSSS) 
(aka Ritter disease) 
Nikolsky positive 
Clinical 
• Typically occurs 3 to
Staphylococcal Scalded Skin Syndrome ... oxacillin (or any anti-staphylococcal ... CA-MRSA or initial treatment ... Scalded #Skin #Syndrome