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differential causes pediatrics thrombocytosis approach blood cancer child classification diffuse disorders emesis extravascular hemolysis intravascular lad leukemoid leukocytosis limping markers
Approach to Leukocytosis - Differential Diagnosis Algorithm Features of hematologic malignancy: • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
Approach to Leukocytosis ... Algorithm Features ... immunosuppression • Exam: lymphadenopathy ... hepatomegaly • Labs: anemia ... #Algorithm #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Overall Approach ... Diagnosis Algorithm ... Blood Loss • Acute ... #Algorithm #Causes ... #Hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... Algorithm Spurious ... Infectious: • Acute ... Iron deficiency anemia ... #Algorithm #Causes
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... Algorithm Decreased ... Normal RBCs • Acute ... #Algorithm #Causes ... #Hematology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Algorithm Reactive ... Fatigue • Acute ... #Algorithm #Causes ... #Hematology #Oncology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Approach to Thrombocytosis ... - Differential Diagnosis ... Algorithm Peripheral ... , deficiency anemia ... #Algorithm #hematology
Lymphadenopathy - Differential Diagnosis Algorithm Localized: • Cervical: EBV, CMV, HIV, Toxo, TB, Lymphoma, Head /
Lymphadenopathy ... - Differential Diagnosis ... Algorithm Localized ... • Infection: Acute ... #Algorithm #Causes
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Algorithm Acute ... ALL) - PAS, TdT Lymphadenopathy ... Pelger-Huet, Macrocytic anemia ... Blood #Disorders #hematology ... #Algorithm
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Algorithm Extravascular ... immune-complex hemolytic anemia ... • Acute HTR ... #Algorithm #Causes ... #Hematology
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY RED FLAGS - In all cases there are specific markers which
FLAGS - In all cases ... pallor, bruising, lymphadenopathy ... #Limping #NWB #Algorithm ... Pathway #Child #Peds ... #Pediatrics #Diagnosis
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