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diagnosis differential management criticalcare hematology hyperkalemia anemia cardiology treatment bilirubin chatter clinica coagulation congenital cord deficiency dic disorders disseminated dm2
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care TRICC - NEJM 1999 -
Major Clinical Trials ... Thresholds in Critical ... blood is a liquid ... Blood saves lives ... unnecessary and cause
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
Causes of False ... Elevation == Decreased ... Content • RBC Transfusions ... turnover • Acute blood ... loss • Hemolytic
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... Transfusion Thresholds ... Causes purpura & ... TRALI): Leading cause ... more likely to cause
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
Differential Diagnosis Algorithm ... • Peripheral blood ... disease, drugs, transfusions ... Differential #Diagnosis #Algorithm ... #causes
Causes of HyperKalemia - Differential Diagnosis Increased extracellular K+: • Tissue injury • Hemolysis • Rhabdomyolysis •
Causes of HyperKalemia ... Tissue injury • Hemolysis ... dietary intake • Blood ... transfusion • ... of injection Decreased
Hyperkalemia: Diagnostic algorithm Decreased renal potassium excretion • Acute renal failure • Chronic renal failure • Drugs Increased
Hyperkalemia: Diagnostic algorithm ... Decreased renal ... Potassium-rich diet • Blood ... transfusion • ... Tumor lysis/hemolysis
Causes of Iron Deficiency - Differential Diagnosis Algorithm • Blood loss: GI (cancer, ulcer, IBD), GU
Causes of Iron Deficiency ... • Blood loss: ... Intravascular hemolysis ... MALABSORPTION • Decreased ... #Fe #algorithm
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
ABO incompatible blood ... transfusion • ... organ damage Clinical ... Treat primary cause ... hydration • RBC transfusion
Hematology Algorithms Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... characterized by a decrease ... However, these thresholds ... well as varying clinical ... These causes could
Inherited Non-hemolytic Disorders of Hyperbilirubinemia == Disorders of Conjugation == Gilbert Syndrome: • 5-10% of the population
Inherited Non-hemolytic ... without evidence of hemolysis ... as jaundice on clinical ... and stress may cause ... bilirubin in the blood
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