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diagnosis anemia hematology hyperkalemia classification hemolysis bilirubinemia deficiency dm2 elderly elevation endocrinology extravascular falls false fe geriatrics hba1c hepatology hgba1c
Hemolysis Classification - Intrinsic and Extrinsic Causes Commentary: Another way to think of immune hemolysis would be
Extrinsic Causes ... , hemolytic transfusion ... #Extrinsic #Differential ... #Diagnosis #Causes ... #Algorithm
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
Causes of False ... Elevation == Decreased ... Content • RBC Transfusions ... blood loss • Hemolytic ... #DM2 #Differential
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... Intrinsic Causes ... elliptocytosis Extrinsic ... prosthetic valve • Transfusion
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... HUS) • Other: Transfusion ... reaction • Intrinsic ... Extravascular #Causes ... #differential #
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
- Differential ... Diagnosis Algorithm ... disease, drugs, transfusions ... #Anemia #Differential ... #causes
Causes of Falls in the Elderly - Differential Diagnosis Algorithm - Intrinsic Factors - Presyncope / Syncope
Causes of Falls ... Diagnosis Algorithm ... • Weakness • Decreased ... Arthritis - Extrinsic ... #Causes
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... Volume (MCV) - Differential ... Diagnosis Algorithm ... Decreased WBCs ... - Decreased/NormaI
Causes of HyperKalemia - Differential Diagnosis Increased extracellular K+: • Tissue injury • Hemolysis • Rhabdomyolysis •
Causes of HyperKalemia ... - Differential ... Tissue injury • Hemolysis ... intake • Blood transfusion ... of injection Decreased
Hyperkalemia: Diagnostic algorithm Decreased renal potassium excretion • Acute renal failure • Chronic renal failure • Drugs Increased
Hyperkalemia: Diagnostic algorithm ... Decreased renal ... diet • Blood transfusion ... • Tumor lysis/hemolysis ... nephrology #potassium #differential
Jaundice - Differential Diagnosis Algorithm Pre-Hepatic - Unconjugated Hyperbilirubinemia Increased Production • Hemolysis • Ineffective Erythropoiesis • Hematoma Decreased
Jaundice - Differential ... Diagnosis Algorithm ... Production • Hemolysis ... Rifampin) Decreased ... #Causes #Hepatology
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