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clinical diagnosis ultrasound rheumatology lupus aneurysm a4c cardiology echocardiogram erythematosus management abdominal aortic autoantibodies differential systemic aorta associations cardiomyopathy druginduced
Effect of Selected Diseases on Complement Levels - C3, C4 • SLE C3 ↓ C4 ↓↓
Selected Diseases on Complement ... Levels - C3, C4 • SLE ... C3 ↓ C4 ↓↓ • Cryo ... • Infection eg SBE ... ThePeanutKidney #Complement
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Workup: - ANA ... 90% - Low complement ... Workup: - ANA ... 80% - Low complement ... #comparison #table
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Disease Associations ANA ... RA Anti-dsDNA - SLE ... - Drug-induced SLE ... Anti-mitochondrial (AMA ... diseases #diagnosis #table
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE ... are evocative of SLE ... Workup: - ANA ... 80% - Low complement ... management of SLE
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Highly specific for SLE ... searched for when ANA ... higly specific for SLE ... #rheumatology #table ... #ANA
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus Clinical and Immunologic Criteria CLINICAL CRITERIA - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... IMMUNOLOGIC CRITERIA - ANA ... anticoagulant - Low complement ... #Rheumatology #SLE
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... laboratory findings (ANA ... anti-Smith Ab, low complements ... RNP antibodies, Complement ... : Drug induced SLE
Causes of ileitis beyond Crohn’s disease and infections include systemic disorders -spondyloarthropathies, vasculitides, ischemia, and amyloidosis
See below for table ... helpful paper complements ... #Differential #Table
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Rheumatology • Lupus (SLE ... ): ANA (anti-nuclear ... #associations #table
Popliteal Aneurysm on Leg POCUS An 80yo male presented with right leg pain. A DVT ultrasound behind
Aneurysm on Leg POCUS ... was performed (see ... higher risk for an AAA ... have an AAA). ... Aneurysm #Leg #POCUS
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