42 results
Lupus Nephritis Classification Algorithm

#Lupus #Nephritis #Classification #Algorithm #diagnosis #differential #types #rheumatology #nephrology #renal
Lupus Nephritis ... Algorithm #Lupus ... Classification #Algorithm #diagnosis ... differential #types #rheumatology ... #nephrology #renal
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... permeability Diagnosis ... Erythematosus #SLE #CNS ... #neurology #rheumatology ... #cerebritis #diagnosis
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... • Lupus (SLE): ... Peptide (CCP) • Myositis ... #diagnosis #associations ... #table
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
• Transverse myelitis ... pain • Extra-CNS ... disorders (Systemic lupus ... Manifestations #diagnosis ... #neurology #symptoms
Myositis Specific Antibodies (MSAs)

Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE
Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ
Immune Mediated
Myositis Specific ... Inclusion Body Myositis ... MSAs #clinical #diagnosis ... #rheumatology # ... table
Myositis and Myopathies
Polymyositis 
 • Progressive, symmetric muscle weakness 
 • Elevated CK, +Anti-Jo, +Anti-Mi2
Dermatomyositis
Myositis and Myopathies ... Anti-retrovirals, Gemcitabine Lupus ... uncommon 5-15% of lupus ... #differential #diagnosis ... #comparison #rheumatology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
- Diagnosis Manifestations ... anemia 4% - Myositis ... Differential Diagnosis ... Erythematosus #Diagnosis ... #differential #rheumatology
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus
Clinical and Immunologic Criteria

CLINICAL CRITERIA
 - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... Criteria - Systemic Lupus ... SEROSITIS - RENAL - NEUROLOGIC ... hemolytic anemia #Diagnosis ... #Rheumatology #
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
- Differential Diagnosis ... pulmonary etc) • CNS ... -> PNS -> NMJ - ... #Differential #Diagnosis ... #neurology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
Criteria for Systemic Lupus ... Acute cutaneous lupus ... least 2 joints • Neurologic ... Erythematosus #diagnosis ... #rheumatology