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diagnosis differential management causes thrombocytosis uc ulcerative anemia celiac checkpointinhibitor chronic ckd cll deficiency endocrinology ferritin gastroenterology gastronintestinal hemodialysis immune
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Differential Diagnosis Algorithm ... Inflammatory: • IBD ... disorders • Celiac disease ... effect following treatment ... Differential #Diagnosis #Algorithm
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Differential Diagnosis Algorithm ... for workup, including ... Rebound effect from treatment ... Vasculitides, IBD ... , Celiac disease
Suspected Celiac Disease - Diagnosis Algorithm Celiac disease suspected: • Signs and symptoms of celiac disease •
- Diagnosis Algorithm ... unresponsive to treatment ... Addisons, microscopic colitis ... Inflammatory (IBD ... #Diagnosis #Algorithm
Relapsing Acute Severe Ulcerative Colitis - Management Algorithm Loss of Response: • (Re)consult Colorectal Surgery • Assess
Severe Ulcerative Colitis ... Adherence • Assess Disease ... up • Surgery ≠ Treatment ... Relapsing #Ulcerative #Colitis ... #IBD #Treatment
Mild-to-Moderate Ulcerative Colitis - Management Algorithm Curcumin: • Natural phytochemical from turmeric • 2g/day divided in 2-3
Mild-to-Moderate Ulcerative Colitis ... placebo • Potential GI ... dosing if liver disease ... #Ulcerative #Colitis ... #treatment #IBD
Iron Deficiency Anemia - Differential Diagnosis Algorithm Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR • Blood loss:
Differential Diagnosis Algorithm ... • Blood loss: GI ... Structural: Celiac disease ... Tropical sprue, IBD ... #ferritin #hematology
Short Stature - Differential Diagnosis Algorithm Normal Variant, Normal Puberty Onset (BA = CA) • Familial Short
Differential Diagnosis Algorithm ... • Cushing's Disease ... Panhypopituitarism Treatment ... • GI (e.g. ... Celiac, IBD) •
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
cells can indicate disease ... microglobulin Treatment ... acute leukemia • GI ... Contamination, colitis ... #oncology #hematology
Occult and Lower Gastronintestinal Bleed - Differential Diagnosis Algorithm Occult (Stool + Occult blood and/or iron deficiency
Differential Diagnosis Algorithm ... , asymptomatic IBD ... OUT BRISK Upper GI ... bleed, • Acute colitis ... Inflammatory Bowel Disease
Immune Checkpoint Inhibitor-Mediated Colitis Grade of Disease Severity: • G1: Increase < 4 BMs/day over baseline; mild
Inhibitor-Mediated Colitis ... Grade of Disease ... -4 • Consult GI ... diagnosis #management #algorithm ... #IBD
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