12 results
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
Liver Enzymes (LFTs ... Liver Injury ... #Enzymes #LFTs ... Transaminitis #diagnosis #differential ... #hepatology
Evaluation abnormal liver tests in pregnancy
- Cholestatic Pattern
- Hepatocellular Pattern

#LFTs #transaminits #pregnancy #obgyn #obstetrics #hepatology #diagnosis
Evaluation abnormal liver ... Cholestatic Pattern - Hepatocellular ... Pattern #LFTs ... obgyn #obstetrics #hepatology ... #diagnosis #differential
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
(LFTs) Elevation ... ) vs Indirect (Hemolytic ... ) Hepatocellular ... ALP) ≥5: Hepatocellular ... #FunctionTest #LFTs
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Hepatocellular Liver ... Injury - Differential ... Liver Injury Differential ... #hepatology #algorithm ... Transaminitis #LFTs
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs ... ALP) • R > 5: Hepatocellular ... #diagnosis #differential ... #Hepatology #transaminitis ... #LFTs #RValue #
Pancytopenia - Differential Diagnosis Algorithm
 • 12-13 g/dL,
 • ANC < 1800/uL,
 • platelet < 150,000/uL

Initial
/uL Initial Workup ... reticulocyte count, LFTs ... ↑ Destruction (hemolysis ... Diagnosis #Algorithm #hematology ... #workup
Liver Function Tests (LFTs) - Normal Values and Interpretation

Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
(LFTs) - Normal ... intrahepatic cholestasis, hepatocellular ... Overproduction (hemolysis ... Function #Tests #LFTs ... Interpretation #diagnosis #hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Chronic - ongoing ↑ LFTs ... or symptoms of liver ... Calculate R-Value • Hepatocellular ... Idiosyncratic #differential ... gastroenterology #hepatology
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver ... 2-5x normal - Hemolysis ... #Injury #hepatology ... #LFTs #transaminitis ... #differential #
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... Thrombosis, Emboli Hepatocellular ... Bilirubin: RBC (hemolysis ... injury #hepatitis #differential ... diagnosis #algorithm #hepatology