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diagnosis hematology algorithm cardiology iron thrombocytosis thrombosis venous anemia cardiomyopathy chf clinical clots embolism extremity fat fatigue ferritin fever gangrenosum
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Thrombosis - Differential ... Ischemic Liver, IBD ... coagulation and other causes ... pathophysiology #hematology ... #differential #
Causes of Arterial and Venous Thrombosis - Differential Diagnosis Framework STRUCTURAL: - PFO: paradoxical emboli - Popliteal
Causes of Arterial ... Venous Thrombosis - Differential ... artery aneurysm: Causes ... Lipoprotein a ↑ - IBD ... Diagnosis #clots #hematology
Fatigue and IBD Algorithm • 40-50% patients have fatigue despite clinical remission • Risk factors: BMI,
Fatigue and IBD ... UC Anemia and IBD ... IDA and active IBD ... fatigue w/ active IBD ... /other causes •
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... - Differential ... Inflammatory: • IBD ... malignancy • Iron deficiency ... #Hematology
Iron Deficiency Anemia - Differential Diagnosis Algorithm Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR • Blood loss:
Anemia - Differential ... Tropical sprue, IBD ... Bypass surgery, Bacterial ... #Anemia #Differential ... Algorithm #ferritin #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... Acute hemolysis, deficiency ... Vasculitides, IBD ... infections, TB, Acute bacterial ... Thrombocytosis #Platelets #Differential
Causes of Fat Malabsorption - Differential Diagnosis Biliary Duct Obstruction • Autoimmune— PBC, PSC • Infection— liver
Causes of Fat Malabsorption ... - Differential ... • Autoimmune— Crohn's ... Pancreatic lipase deficiency ... Celiac disease • IBD
Iron Deficiency in Heart Failure Pathophysiology: Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Iron Deficiency ... ng/mL (absolute ID ... 20% (functional ID ... heartfailure #diagnosis #management ... #cardiology
Leg Pain - Differential Diagnosis Framework Bone/Joint Causes of Leg Pain: • Fracture • Arthritis • Gout/pseudogout
Leg Pain - Differential ... • Bursitis • IBD ... ulcers, Edema Arterial ... Vit B12, B6, Cu deficiency ... #Leg #pain #differential
Fever Patterns - Differential Diagnosis Framework Continuous Fever: Temp > 38°C with only 1 degree fluctuation in 24
Fever Patterns - Differential ... Still's disease • Crohn ... Non-Infectious Causes ... arthritis • Crohn's ... fever • Hyper-IgD
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