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diagnosis differential nephrology clinical hematology classification rheumatology glomerulonephritis management pulmonary workup algorithm anemia causes ceap chronic disorders erythematosus hemolytic lupus
Effect of Selected Diseases on Complement Levels - C3, C4 • SLE C3 ↓ C4 ↓↓
Complement Levels - C3 ... , C4 • SLE C3 ... • MCGN type 1 C3 ... ↓ C4 ↓↓ • Cryo ... C3 ↓ C4 ↓↓ •
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
immunotactoid GN, Type I cryo ... monoclonal Ig deposits, C3
Glomerulonephritis - Differential Diagnosis Framework ANCA: • C-ANCA: GPA (Wegener's) • P-ANCA: Microscopic Polyangiitis, Eosinophilic GPA (Churg
Mediated: • ↓C3 ... Cryoglobulinemia • Normal C3
Autoimmune Hemolytic Anemia (AIHA) Pathophysiology - Warm vs Cold AIHA Warm AIHA: - 70%; IgG mediated -
IgG positive, C3 ... IgG negative, C3
Herpes Zoster C3 Distribution: Dermatomally distributed vesicles, many of which have coalesced, in patient with HZV
Herpes Zoster C3 ... HZV #Dermatomal #C3
Warm vs Cold Autoimmune Hemolytic Anemia Warm Autoimmune Hemolytic Anemia: • Mechanism: IgG and Complement-mediated • Etiology:
positive for IgG +/- C3 ... Coombs Positive for C3
C3-C7 Fractures and Injuries - Which Fractures are Stable and Unstable #Diagnosis #Orthopedics #C3C7 #Cervical #Fractures #Unstable
C3-C7 Fractures
CEAP Classification of Chronic Venous Disorders C1: Telangiectasia, Reticular Veins C2: Varicose Veins C3: Edema C4a: Pigmentation and/or eczema C5: Healed
Varicose Veins C3
Subtypes of Serum Proteins Pre-albumin (Transthyretin) Albumin Globulins • Alpha-1: Alpha-1 antitrypsin, Serum amyloid A, Ceruloplasmin, Corticosteroid-binding globulin (Transcortin),
Angiotensinogen • Beta: C3
Staphylococcus-associated GlomeruloNephritis - Diagnosis and Management Summary CLINICAL • Nephritic syndrome (Casts) • Marked proteinuria (may be
DIAGNOSIS • 80% ↓ C3 ... exudative GN • C3
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