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Cutaneous Manifestations of Monoclonal Gammopathy • Extravascular lg Deposits: Systemic amyloidosis, Nodular amyloidosis, Macroglobulinoderma, Follicular hyperkeratotic
Xanthomatosis • Cytokine ... secretion: POEMS syndrome ... , Syndrome Schnitzler ... cutis laxa, TEMPI syndrome
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation Syndrome ... pro-inflammatory cytokines ... hemophagocytosis and cytokine ... Periodic fever syndromes ... hypersensitivity syndromes
KSHV Inflammatory Cytokine Syndrome (KICS) By Dr. Sara Dong @swinndong via #IDFellowCase #ID #Infectious Diseases
KSHV Inflammatory Cytokine ... Syndrome (KICS)
Cardiorenal Syndrome (CRS) Types • Type 1 - Acute CRS: Alteration of renal perfusion is the
Cardiorenal Syndrome ... micro-circulatory dysfunction, cytokine ... #Cardiorenal #Syndrome
Streptococcal Toxic Shock Syndrome (STSS) Complication of invasive GAS disease characterized by shock & MOF → occurs
Streptococcal Toxic Shock Syndrome ... of inflammatory cytokines ... #Toxic #Shock #Syndrome
Anti-IL6 Agents (Tocilizumab, Siltuximab) in COVID19 IL-6 activates T cells and macrophages, among other cell types (see
cell types (see “Cytokine ... Activation Syndrome
KSHV Inflammatory Cytokine Syndrome (KICS) Working Case Definition for KICS: Requires at least 2 clinical manifestations (from
KSHV Inflammatory Cytokine ... Syndrome (KICS) ... #Inflammatory #Cytokine ... #Syndrome #Kaposi
Fever vs Hyperthermia Fever: • Regulated in the hypothalamic thermoregulatory center • "Set point" raised by prostaglandin
Endotoxins, Toxins, Cytokines ... Neuroleptic malignant syndrome ... ; Serotonin syndrome
Approach to Undifferentiated Shock - OnePager Summary Shock occurs when there is inadequate blood flow (CO) &
CCB, BB, BRASH syndrome ... fat embolism, cytokine ... release syndrome
Kounis Syndrome Acute coronary syndrome (symptoms such as chest pain relating to reduced blood flow to the
Kounis Syndrome ... Acute coronary syndrome ... of inflammatory cytokines ... Diagnosis #Kounis #Syndrome
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