27 results
diagnosis hematology causes algorithm hemolytic hemolysis infectiousdiseases management rheumatology cardiology endocarditis extravascular intravascular lung oncology vasculitis workup abscess acidosis agglutinin
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
- Differential ... Diagnosis Algorithm Signs ... Hypersplenism, Infection ... #Differential # ... Diagnosis #Algorithm #hematology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... • Membrane defects ... drug induced • Infections ... Diagnosis #causes #classification ... #hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Volume (MCV) - Differential ... Inflammation, Chronic Infection ... #MCV #Classification ... #Differential # ... Algorithm #Causes #Hematology
Anaplasma Infection - Anaplasma phagocytophilum Pathophysiology: • Obligate, intracellular bacteria • Transmitted via blacklegged tick —
Anaplasma Infection ... scapularis • Infects ... within morulae Signs ... myalgias, shaking chills ... immature forms) • Anemia
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Internal (RBC) - Infections ... : Sickle cell anemia ... #Hemolysis #Differential ... #Diagnosis #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Intravascular Hemolysis - Differential ... circulation - Infections ... immune-complex hemolytic anemia ... Extravascular #Differential ... Algorithm #Causes #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Microangiopathic hemolytic anemia ... Intrinsic RBC Defects ... Extravascular #Causes #differential ... #diagnosis #hematology ... #anemia
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
(e.g. cancer, infection ... Intrinsic RBC defects ... G6PD deficiency), Infections ... Production #Index #hematology ... #anemia #differential
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... inclusions - If infection ... ARUPLabs #Hemolytic #Anemia ... #Differential #
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... - Hemolytic anemia ... SLE) - Viral infections ... APLS • Acute Infectious ... #nonpalpable #dermatology
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