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differential symptoms classification management neurology ana anca antibodies antibody antineutrophil antinuclear aortitis autoantibodies bruising cerebritis cns cryoglobulinemia cryoglobulins diseases manifestations
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Lupus (SLE) General ... #Lupus #SLE #systemic ... #erythematosus ... #signs #symptoms ... #diagnosis #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Neurological 12% - Thrombocytopenia ... #Systemic #Lupus ... #signs #symptoms ... #differential #rheumatology
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
- Differential Diagnosis ... Arthritis (RA), Systemic ... lupus erythematosus ... (SLE), Sarcoidosis ... #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Lupus Erythematosus ... Cerebrovascular Disease ... #Lupus #Erythematosus ... #SLE #CNS #neurology ... #rheumatology #
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
antibodies) • Systemic ... lupus erythematosus ... in drug-induced SLE ... Antineutrophil #antibodies #diagnosis ... #rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... as systemic lupus ... purpura: strong sign ... , and SLE) • Urinalysis ... #rheumatology #
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
Causes of Purpura ... systemic lupus erythematosus ... Congenital heart disease ... infections - Vasculitis ... peds #pediatrics #diagnosis
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
pain • Extra-CNS complications ... autoimmune disorders (Systemic ... lupus erythematosus ... Manifestations #diagnosis ... #signs
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... • Autoimmune diseases ... : - 10% SLE or ... lupus erythematosus ... classification #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
as SLE, atherosclerotic ... purpura: Strong sign ... ischemia • Skin: Erythematous ... tract, and often causes ... #Rheumatology
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