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diagnosis erythematosus systemic differential syndrome ana antinuclear druginduced signs symptoms thrombocytopenia antibodies autoantibodies classification criteria disease heparin hit nephrology patterns
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
erythematosus (SLE ... disease (MCTD), Drug-induced ... Idiopathic Arthritis ... erythematosus (SLE ... ANA #patterns #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... vs SLE Drug Induced ... Constitutional symptoms, Arthritis ... #table #rheumatology ... #diagnosis #management
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... Initial screening test ... severe disease Treatment ... Summary #diagnosis #rheumatology ... #management
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
disease (MCTD), Drug-induced ... Idiopathic Arthritis ... , Drug-Induced Lupus ... Cirrhosis, Drug-Induced ... ANA #patterns #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... #CNS #neurology ... #rheumatology # ... cerebritis #diagnosis #management ... #treatment
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus Clinical and Immunologic Criteria CLINICAL CRITERIA - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... SEROSITIS - RENAL - NEUROLOGIC ... Direct Coombs’ test ... #Diagnosis #Rheumatology ... #SLE #Lupus #Erythematosus
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
• Arthritis domain ... least 2 joints • Neurologic ... pericarditis • Hematologic ... Classification #Criteria #SLE ... Erythematosus #diagnosis #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... and Management ... , oral ulcers, Lupus ... life-threatening • Treatment ... #Summary #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Manifestations: - Arthritis ... involvement 3% SLE-Related ... Mimickers: Drug-induced ... Lupusreference #SLE ... #differential #rheumatology
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Farr assay) and lupus ... 60-70%) & drug-induced ... , neonatal lupus ... clinically suspected, tests ... erythematosus #diagnosis #rheumatology
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