19 results
Causes of Hypernatremia - Differential Diagnosis
Inadequate water intake:
 • Lack of access to water
Extrarenal hypotonic fluid
- Differential ... perspiration Renal ... concentrating defect: • Diuretics ... • Osmotic diuresis ... #nephrology #sodium
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Differential Diagnosis ... • Euvolemic (Low ... • Hypovolemic: Diuretics ... osmotic (solute) diuresis ... #sodium
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
Sodium loss (diuretics ... deficiency, Post-AKI diuresis ... (AKI, Post-AKI diuresis ... #differential # ... #sodium #nephrology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Diuretics and Agents ... irrigation • Management ... Torsemide) • Acute pulmonary ... #Diuresis #Nephrology ... #Pharmacology #Medications
Modified Hyponatremia Algorithm
Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants
Hypotonic Hyponatremia: 
 • ADH ON (UOsm > 100):
> 30): SIADH, Medications ... (diuretics), Hypothyroidism ... Primary polydipsia, Low ... #Algorithm #diagnosis ... #sodium #nephrology
Causes of Hypernatremia - Differential Diagnosis Algorithm
Hypernatremia - Excess free water loss, Serum Sodium >145 mmol/L
High
- Differential ... water loss, Serum Sodium ... administration • Osmotic diuresis ... mannitol, glucosuria Low ... #Nephrology #Differential
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
- Differential ... • Drugs • Pulmonary ... GI losses • Renal ... especially thiazide diuretics ... #Nephrology #Differential
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
- Differential ... • Drugs • Pulmonary ... GI losses • Renal ... especially thiazide diuretics ... #Nephrology #Differential
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Hypokalemia - Differential ... Diagnosis Algorithm ... Thyrotoxicosis Medications ... • Discontinued diuretic ... #nephrology #low
Drugs associated with hypokalemia and hypomagnesemia

Hypokalemia
- Shift from extracellular fluid to intracellular fluid compartment
  -
overdose) - Sodium ... foscarnet - Diuretics ... and other loop diuretics ... antiretroviral therapy - Diuretics ... diagnosis #nephrology