38 results
Diuretics sites of action on the nephron
1) Acetazolamide (carbonic anhydrase inhibitor)
2) Osmotic diuretics (e.g. mannitol)
3) Loop
(e.g. ... Metolazone) 5) Potassium-sparing ... diuretics (e.g. ... #pharmacology #nephrology ... #medications #sites
Summary of Diuretic Agents 
Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction
CARBONIC ANHYDRASE
Summary of Diuretic ... Chlorthalidone POTASSIUM-SPARING ... #Medications #Pharmacology ... #summary #table ... #nephrology
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
- Differential Diagnosis ... Thyrotoxicosis Medications ... • Discontinued diuretic ... #Algorithm #nephrology ... #low #potassium
Diuresis in Critical Care - Achieving a Negative Fluid Balance
Advantages Of A Negative Fluid Balance:
 •
in the later (e.g ... CONCENTRATION MEDICATIONS ... ) to normalize Potassium ... Early nephrologv ... Fluid #Balance #management
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
- Differential Diagnosis ... Algorithm Extra-renal ... Loop and thiazide diuretics ... #potassium #low ... #nephrology
Diagnostic Algorithm for the Patient with Seizure in the Emergency Department
Does the history suggest a seizure?
Diagnostic Algorithm ... additional symptoms (eg ... speech abnormality, etc ... Postictal state #Algorithm ... #management #Neurology
Polyuria - Differential Diagnosis Algorithm
Polyuria = >3L Urine output / 24 hours
Urine osmolality = 2 (Na
- Differential Diagnosis ... Algorithm Polyuria ... mosm/kg • Solute Diuresis ... solute intake (e.g ... #Algorithm #nephrology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Diuretics and Agents ... disequilibrium syndrome • Diagnosis ... irrigation • Management ... #Nephrology #Pharmacology ... #Medications #Table
Hypokalemia Differential Diagnosis Algorithm
Hypertensive:
 • High Al, Low R - Primary aldosteronism
 • High Al, High
Hypokalemia Differential Diagnosis ... Algorithm Hypertensive ... >20 mEq/24 h - Diuretics ... #Algorithm #nephrology ... #causes #low #potassium
Modified Hyponatremia Algorithm
Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants
Hypotonic Hyponatremia: 
 • ADH ON (UOsm > 100):
Modified Hyponatremia Algorithm ... > 30): SIADH, Medications ... (diuretics), Hypothyroidism ... #diagnosis #sodium ... #nephrology