28 results
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
distinction has HUGE treatment ... and first-line treatment ... Microangiopathy #thrombocytopenic ... Comparison #Diagnosis #Table ... #Hematology
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table

 • Thrombotic Thrombocytopenic Purpura (TTP)
Differential Diagnosis Table ... • Thrombotic Thrombocytopenic ... Purpura (TTP) ... Metabolism-mediated TMA - Coagulation-mediated ... Microangiopathy #TMA #hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Autoimmune • ITP ... HELLP Syndrome • TTP ... Heart Valve) #Thrombocytopenia ... Algorithm #Causes #Hematology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Thrombocytopenia ... and Pregnancy - TTP ... presents with coagulation ... AFLP #obstetrics #hematology ... #diagnosis #table
Treatment of Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis of TTP:
 • Rare and severe, ADAMTS13 deficiency
 • Autoimmune
Treatment of Thrombotic ... Thrombocytopenic ... HUS) Treatment ... Thrombotic #Thrombocytopenic ... hematology
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Thrombocytopenia ... presents with coagulation ... of child 3) TTP ... Obstetrics #OBGyn #Hematology ... Diagnosis #Comparison #Table
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
inflammation • Thrombocytopenia ... Primary Causes: - Thrombocytopenia ... disease - DIC/TTP ... Differential #Diagnosis #hematology ... #nonpalpable #dermatology
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... NSAIDs, quinine, etc ... Microangiopathy: DIC, TTP ... Medicine @SCVMCMed #Thrombocytopenia ... Diagnosis #Framework #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
• TMA’s (HUS/TTP ... Schistocytes - MAHA: TTP ... + Bleeding Treatment ... diagnosis #causes #treatment ... #management #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Non malignant hematologic ... effect following treatment ... of ITP • Rebound ... following EtOH induced thrombocytopenia ... Algorithm #Causes #Hematology