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diagnosis rheumatology algorithm autoimmune hemolytic oncology causes classification signs symptoms syndrome abscess acidosis acquired adultonset agglutinin aiha antibody apml arteritis
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
DIAGNOSE AIHA • Anemia ... • IgG type ± C3d ... • Blood smear: Differential ... #diagnosis #management ... #treatment #rheumatology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... HELLP - Grafts, Valves ... Drug-associated, PCH ... Defects: Sickle cell anemia ... #Diagnosis #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
• Symptoms of anemia ... • hemolytic anemia ... younger pts) Differential ... #hemolytic #anemia ... #hematology #diagnosis
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
fraction < 20% Differential ... Muscular: normal CK ... hepatitis • Pulmonary ... #diagnosis #management ... #treatment #rheumatology
Autoimmune Hemolytic Anemia (AIHA) Treatment Warm AIHA: 1) Steroids - 1-2 mg/kg prednisone daily • Until
Autoimmune Hemolytic Anemia ... (AIHA) Treatment ... esp if severe disease ... , Splenectomy, MMF ... #management #hematology
Non-alcoholic fatty liver disease algorithm. For those patients with NAFLD or liver disease of unknown aetiology,
fibrosis score with values ... markers such as ELF ... 4, fibrosis-4; HCC ... algorithm #Referral #Management ... #Hepatology
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
Leukocytosis, anemia ... Clindamycin in case of PCN ... Lung Abscess Differential ... Lung #Abscess #pulmonary ... #differential #
Chest Pain Diagnosis and Management Algorithm STEMI: - Hx: Pressure like CP, Radiation to arm/jaw, CAD risk
Diagnosis and Management ... Radiation to arm/jaw, CAD ... Limb ischemia Pulmonary ... COPD, asthma, CF, PCP ... #Algorithm #differential
Hemorrhagic Pericardial Effusions (Hemopericardium)- Differential Diagnosis Framework IATROGENIC DISEASE Secondary to invasive cardiac procedures NONIATROGENIC • Malignancy (e.g., metastatic spread:
Hemopericardium)- Differential ... IATROGENIC DISEASE ... patients with pulmonary ... amyloidosis • Uremia ... RA, and other CTD
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Imaging: CXR- pulmonary ... initiation • Differential ... fluid overload, PCC ... APML #diagnosis #management ... #hematology #oncology
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