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diagnosis differential causes algorithm rheumatology management peds dermatology disease clinical hepatology signs sle symptoms systemic treatment acute anemia arthritis constipation
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
(usually IgG) (e.g ... . lupus, CLL, lymphoma ... (usually IgM) (e.g ... deficiencies (e.g ... differential #diagnosis #hematology
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
• Thrombus (e.g ... Myeloproliferative disorders (eg ... Inflammatory • Systemic Lupus ... Algorithm #Causes #Hematology
Short Stature - Differential Diagnosis Algorithm Normal Variant, Normal Puberty Onset (BA = CA) • Familial Short
Dysplasias • (e.g ... Disease • GI (e.g ... IBD) • Renal (e.g ... • CNS Tumors (e.g ... endocrinology #causes #pediatrics
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic Lupus ... Demyelinating Syndrome ... Diagnosis of Lupus ... Lumbar Puncture, EEG ... CNS #neurology #rheumatology
Common causes of Acute Kidney Injury AKI - Differential Diagnosis HEMODYNAMIC • Cardiac failure: Impaired forward flow,
vasoconstriction (e.g ... inhibitors, hepatorenal syndrome ... disease or drugs e.g ... Post-infectious GN, Lupus ... AIN) • Drugs (e.g
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Toxic Damage (e.g ... Displacement (e.g ... Non-lmmune: • HELLP Syndrome ... Foreign Surface (e.g ... Algorithm #Causes #Hematology
Causes of Pediatric Constipation - Differential Diagnosis Algorithm Dietary / Functional: • Insufficient Volume / Bulk Neurologic: •
Causes of Pediatric ... Withholding • Painful (e.g ... Guillain-Barré Syndrome ... #Causes #Peds #Pediatrics
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis • Infection: Extrapulmonary tuberculosis, Abscess, Endocarditis,
Infected thrombosis, (e.g ... Lemierre's syndrome ... Malignancy: - Hematologic ... Inflammatory Diseases (e.g ... . autoimmune): Lupus
Characteristic features of the rash are: -Rough texture (like sandpaper) -Worse in the skin folds e.g. groin, axilla,
the skin folds e.g ... ) #Clinical #Dermatology ... #Peds #Pediatrics
Causes of Developmental Delay - Differential Diagnosis Algorithm Isolated Domain Delay - Reduced Respiratory Drive: • Cognitive
Developmental Delay: • Syndromic ... Teratogenic Disorder (e.g ... Landau-Kleffner Syndrome ... • Mechanical (e.g ... #Causes #Peds #Pediatrics
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