22 results
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
Microangiopathy #thrombocytopenic ... HemolyticUremicSyndrome #HUS ... #thrombocytopenia ... #Comparison #Diagnosis ... #Table #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Megakaryopoiesis • Aplastic Anemia ... HELLP Syndrome • TTP ... /HUS • DIC • ... #Hematology
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table

 • Thrombotic Thrombocytopenic Purpura (TTP)
- Differential Diagnosis ... Table • Thrombotic ... Thrombocytopenic ... Purpura (TTP) ... Microangiopathy #TMA #hematology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Thrombocytopenia ... and Pregnancy - TTP ... /HUS, HELLP Syndrome ... #diagnosis #table ... #comparison
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... - Differential Diagnosis ... Microangiopathy: DIC, TTP ... , HUS - Antibody-mediated ... #Framework #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... disease - DIC/TTP ... /HUS - Hemolytic ... anemia - Splenomegaly ... #nonpalpable #dermatology
Thrombotic Microangiopathy - TMAs
1. Not all MAHAs are due to TMAs but (almost) all TMAs cause
almost) all TMAs cause ... triad of MAHA + thrombocytopenia ... Microangiopathy #TMAs #hematology ... #diagnosis #ttp ... #hus
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Thrombocytopenia ... child * Severe cases ... of child 3) TTP ... #Diagnosis #Comparison ... #Table
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... : • MAHA: TTP, ... HUS, DIC, HELLP ... #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... microangiopathy: Thrombotic thrombocytopenic ... purpura (TTP), ... uremic syndrome (HUS ... #hematology #anemia