21 results
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... → Refer to hematology ... hemolysis, deficiency anemia ... • Reaction to Medications ... Diagnosis #Algorithm #hematology
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
HIV/HCV co-infection ... vertical transmission prophylaxis ... HBV infection with ... > 3 mg/dL) or acute ... #management #hepatology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Pseudotumor - Infectious ... • CMV • HIV ... History of Bleeding, Infection ... Fatigue • Acute ... Algorithm #Causes #Hematology
Causes of Neutrophilia - Increased Neutrophils - Differential Diagnosis Algorithm
Infection
 • Bacterial
 • Abscess
 • Viral
Medications
Neutrophils - Differential ... Diagnosis Algorithm Infection ... Abscess • Viral Medications ... Polycythemia vera Acute ... Algorithm #Causes #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Thrombocytopenia - Differential ... Megakaryopoiesis • Aplastic Anemia ... Quinidine • HIT ... Vasculitis • Infection ... Algorithm #Causes #Hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Thrombocytosis - Differential ... Myelofibrosis Infectious ... : • Acute or Chronic ... Iron deficiency anemia ... Algorithm #Causes #Hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
(e.g. cancer, infection ... Index > 3: • Acute ... G6PD deficiency), Infections ... Production #Index #hematology ... #anemia #differential
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Thrombocytosis - Differential ... Thrombocytosis): • Acute ... infection • Solid ... malignancies • Anemia ... Diagnosis #Causes #hematology
Etiologies of Peripheral Neuropathy
 • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism
 • Medication-induced: ART, Antibiotics,
Hypothyroidism • Medication-induced ... Chemotherapy • Infectious ... : HIV, Hepatitis ... Fabry's disease, Acute ... Peripheral #Neuropathy #differential
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... drug induced • Infections ... #Differential # ... classification #hematology