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diagnosis hemolysis algorithm causes deficiency extravascular intravascular management oncology agglutinin anemias autoimmune cellulitis champs chronic classification clinical cll cold common
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table Warm AIHA (48-70%) Cold AHA (16-32%) • Donath-Landsteiner HA (paroxysmal
Autoimmune Hemolytic ... Anemia (AIHA) - ... Table Warm AIHA ... #Anemia #AIHA # ... #Table #hematology
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Hemolytic Anemias ... - Differential ... Anemias (AIHAs) ... #Anemias #Differential ... Diagnosis #Algorithm #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
- Differential ... • Cold AIHA ... anemia • ... Extravascular #Differential ... Algorithm #Causes #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
anemia): ... - Autoimmune (AIHA ... Extravascular #Causes #differential ... #diagnosis #hematology ... #anemia
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
Differential diagnosis ... formerly known as atypical ... anemia" • HELLP ... #schistocytes #differential ... #diagnosis #hematology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... Hypersplenism • AIHA ... #Anemia #Differential ... classification #hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Autoimmune: Warm AIHA ... Defects: Sickle cell anemia ... #Differential # ... Diagnosis #hematology
Drugs Implicated in Hemolytic Anemia • Hapten (Drug binding to RBC membrane): Penicillin, Cephalosporin, Tetracycline, Tolbutamide,
Anemia • Hapten ... (induction of AIHA ... #Anemia #differential ... #diagnosis #pharmacology ... #table
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
cirrhosis H - Heavy ... angioedema A - Atypical ... atheroembolic, AIHA ... Mnemonic #diagnosis #differential ... #hematology
Iron Deficiency Anemia - Differential Diagnosis Algorithm Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR • Blood loss:
Iron Deficiency Anemia ... - Differential ... extravascular) hemolysis ... Celiac disease, Tropical ... Algorithm #ferritin #hematology
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