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causes algorithm management oncology rheumatology classification rash chronic hemolytic leukemia skin thrombocytosis treatment vasculitis workup cancer cll cutaneous deficiency disease
Approach to Leukocytosis - Differential Diagnosis Algorithm Features of hematologic malignancy: • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
Diagnosis Algorithm ... immunosuppression • Exam: lymphadenopathy ... hepatomegaly • Labs: anemia ... , ↑ MCV, ↑/↓ platelets ... #hematology #WBC
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
- Differential ... Diagnosis Framework ... Macroangiopathic, Infections ... #Differential # ... Diagnosis #hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
- Differential ... Megakaryopoiesis • Aplastic Anemia ... Non-lmmune: • HELLP Syndrome ... Vasculitis • Infection ... #Causes #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Framework Decreased Production: - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
- Differential ... Diagnosis Framework ... infiltration: malignancy, infection ... antiphospholipid syndrome ... #hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Diagnostic Framework ... Myelodysplastic syndrome ... #differential # ... diagnosis #causes ... #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Diagnosis Algorithm ... Myelofibrosis Infectious ... following EtOH induced thrombocytopenia ... Iron deficiency anemia ... #Causes #Hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Corpuscular Volume (MCV ... ) - Differential ... Diagnosis Algorithm ... Inflammation, Chronic Infection ... #Causes #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... Diagnosis and Workup ... procedures - Infection ... anemia (vegan, ... #Workup #hematology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse Lymphadenopathy ... Diagnosis Algorithm ... Pseudotumor - Infectious ... • EBV • CMV ... #Causes #Hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... - Hemolytic anemia ... #Diagnosis #hematology ... #nonpalpable #dermatology
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