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differential algorithm hemolytic pulmonary rheumatology causes infections lung product reactions symptoms treatment workup abscess agglutinin aids alveolar anemias antibody arteritis
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Algorithm Signs ... of anemia and hemolysis ... Immune-mediated Hemolysis ... Nonimmune-mediated Hemolysis ... #hematology
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Anemia 1) DIAGNOSE ... reticulocytes • Hemolysis ... type ± C3d • Blood ... #Anemia #diagnosis ... #management #treatment
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
the peripheral blood ... Retroperitoneal, Uterine • Hemolysis ... Microangiopathic hemolytic ... Production #Index #hematology ... #diagnosis #calculation
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Defects: Sickle cell anemia ... - Peripheral Blood ... Urobilinogen #Hemolysis ... #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
hemorrhage and hemolysis ... intravascular hemolysis ... of Peripheral blood ... the severity of hemolysis ... #Workup #Hematology
Iron Deficiency Anemia - Differential Diagnosis Algorithm Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR • Blood loss:
Iron Deficiency Anemia ... - Differential Diagnosis ... TSAT, sTfR • Blood ... extravascular) hemolysis ... Algorithm #ferritin #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... : Acute blood loss ... , Acute hemolysis ... , deficiency anemia ... #Differential #Diagnosis
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Diagnosis: • hemolytic ... • Compensated hemolysis ... sensitize red blood ... intravascular hemolysis ... #anemia #hematology
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... in peripheral blood ... High in acute blood ... loss, hemolysis ... #Workup #Hematology
Causes of Anemia in Cirrhosis - Differential Diagnosis Framework LOW RETIC INDEX - ↓ PRODUCTION • Vitamin
- Differential Diagnosis ... RETIC INDEX: • Blood ... , Autoimmune hemolytic ... anemia, Hemolysis ... #Hepatology
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