17 results
Tranexamic Acid - Indications and Pharmacology
Pharmacokinetics:
 • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
Tranexamic Acid - Indications ... swelling in w/ hereditary ... angioedema) • ... Hypersensitivity & anaphylaxis ... Tranexamic #Acid #Indications
Vasopressors and Inotropes
 • Norepinephrine - Levophed - "Levo" - Generally thought of as the first
pressor added in shock ... - ACLS (1st), Anaphylaxis ... in refractory shock ... criticalcare #summary #comparison ... #pharmacology #indications
Stridor - Differential Diagnosis Framework:
High-pitched, variable respiratory sound

ETIOLOGIES:
Infectious:
 • Retropharyngeal abscess
 • Acute epiglottitis
 • Peritonsillar
Allergic/Immune: • Anaphylaxis ... • Hereditary ... angioedema Congenital ... malformations • Anaphylaxis ... Tracheal stenosis • Anaphylaxis
Common Vasopressors and Inotropes
Norepinephrine (NE)
 - Indication: Distributive shock (1st line for septic shock), Cardiogenic shock
Norepinephrine (NE) - Indication ... Vasopressin - Indication ... Epinephrine - Indication ... Dobutamine - Indication ... Vasopressors #Inotropes #comparison
Bedside Classification of Shock

Hypovolemic shock 

- Vomiting, diarrhea, overdiuresis 

- Hemorrhage (GI, peritoneal, RP) 

Distributive shock
Classification of Shock ... Hypovolemic shock ... - Septic shock ... Adrenal crisis - Anaphylaxis ... #Cardiogenic #Comparison
Shock and Vasoactive Drugs 
1) Determine type and etiology of shock
 • Distributive: Sepsis, Anaphylaxis, Neurogenic
Shock and Vasoactive ... and etiology of shock ... Distributive: Sepsis, Anaphylaxis ... #Vasopressors #shock ... diagnosis #management #comparison
Manifestations of Anaphylaxis by Body System

Dermatologic/mucosal

 - Eyes: periorbital swelling/erythema, injected conjunctiva, tears

 - Oral mucosa:
Manifestations of Anaphylaxis ... - Oral mucosa: angioedema ... piloerection, angioedema ... : bradycardia, shock ... Signs #Symptoms #Anaphylaxis
Shock Classification and Differential Diagnosis
SHOCK
 • MAP <65, SBP <90, drop in SBP > 40
 •
Shock Classification ... Differential Diagnosis SHOCK ... SVR • Sepsis, Anaphylaxis ... Failure, Toxins/Medications ... Sophia_Hayes_MD #Shock
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
Shock - Differential ... Distributive: Sepsis, Anaphylaxis ... Failure, Toxins/Medications ... Dehydration Shock ... Sophia_Hayes_MD #Shock
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
Female predominance Anaphylaxis ... lesions - Wheals/angioedema ... , Hypotension, shock ... #rheumatology #comparison