21 results
rheumatology differential vasculitis management workup causes classification erythematosus hemolytic huv lupus pulmonary syndrome testing thrombocytopenia urticarial aecopd ahus anemia arthritis
Diagnosis and Management of Hypocomplementemic Urticarial Vasculitis (HUV) Diagnosis of HUV 1) Chronic urticaria 2) Leukocytoclastic vasculitis 3)
of Hypocomplementemic ... ) Diagnosis of ... vasculitis 3) Hypocomplementemia ... TerrierBen #Hypocomplementemic ... #Rheumatology
Pathophysiology of Hypocomplementemic Urticarial Vasculitis C1q/anti-C1q antibiody -> Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Pathophysiology of Hypocomplementemic ... Complex Formation - Complement ... TerrierBen #Hypocomplementemic ... Urticarial #Vasculitis #HUV ... Pathophysiology #Rheumatology
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... A - Atypical HUS ... @AnnKumfer #Hypocomplementemia ... #Low #Complement ... #differential #hematology
Effect of Selected Diseases on Complement Levels - C3, C4 • SLE C3 ↓ C4 ↓↓
Levels - C3, C4 ... • SLE C3 ↓ C4 ... C3 ↓ C4 → • HUS ... #Levels #C3 #C4 ... #differential #diagnosis
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis 90%: -
- Differential Diagnosis ... Levels: SLE, Cryoglobulinemic ... hypertension - MAHA: HUS ... , atypical HUS, ... #Differential #Diagnosis
Atypical HUS - Hemolytic Uremic Syndrome Unlike typical HUS, which is shigatoxin mediated, aHUS is not typically
autoimmune like SLE ... It is complement ... need the ADAMTS13 level ... with Eculizumab (complement ... Uremic #Syndrome #diagnosis
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
- Differential Diagnosis ... Algorithm Decreased ... Autoimmune • ITP • SLE ... Syndrome • TTP/HUS ... #Hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... against MPO • Complement ... (Low levels mixed ... vasculitis, and SLE
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
- Differential Diagnosis ... Algorithm Extravascular ... perfringens - Complement-Mediated ... MAHA (TTP, DIC, HUS ... #Hematology
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus Clinical and Immunologic Criteria CLINICAL CRITERIA - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... CRITERIA - ANA level ... Anti-dsDNA antibody level ... anticoagulant - Low complement ... #Rheumatology #
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