2307 results
Intracranial Hemorrhage (ICH) and Increased Intracranial Pressure (ICP) - Pathophysiology
ICH Management:
1. Manage Blood Pressure
  •
) - Pathophysiology ... ICH Management ... • Spontaneous ICH ... lidocaine, +/- pre-treatment ... #Pathophysiology
Hantavirus
Pathogen: Hantavirus - Rodents are the primary reservoir
Transmission:
 • Shed in the urine, feces, saliva of
• Hantavirus PCR ... • Autopsy PCR ... Treatment: • ... Supportive: ICU ... diagnosis #management #treatment
Bipolar Disorder: Pathogenesis and Clinical Findings
 • Disruption of emotional homeostasis
 • Oscillation between mood states
euphoria - Incr ... grandiosity - Incr ... mood - Primary treatment ... withdrawal - Incr ... MoodDisorders #Diagnosis #Pathophysiology
Pathophysiology of Hypocomplementemic Urticarial Vasculitis

C1q/anti-C1q antibiody ->
Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Pathophysiology ... Mast Cells -> Incr ... inflammatory cells -> Incr ... Vasculitis #HUV #Pathophysiology
Cushing's Reflex - Pathophysiology
HYPERTENSION with a reflex BRADYCARDIA
 → ↑ ICP 
 → ↓ CBF
 →
Cushing's Reflex - Pathophysiology ... BRADYCARDIA → ↑ ICP ... Cushings #Reflex #Pathophysiology
Mechanisms Driving Increased Thrombosis and Bleeding in Liver Disease
Increased Thrombosis 
Increased Platelet-Vesset Wall Interaction 
 •
Interaction • Incr ... Willebrand factor • Incr ... Generation • Incr ... Plasminogen • Incr ... Clot #Cirrhosis #Pathophysiology
Initial treatment of renal bone disease and cinacalcet for secondary hyperparathyroidism
Phosphate binders reduce hyperphosphataemia and hyperparathyroidism.
Initial treatment ... the first-line treatments ... #Pharmacology #Pathophysiology
Pulmonary Hypertension - Treatment, ICU Management and Monitoring

#PHTN #Pulmonary #Hypertension #Treatment #Management #Monitoring #Diagnosis
Hypertension - Treatment ... , ICU Management ... #Hypertension #Treatment
Rheumatoid Arthritis - ACR 2021 Guidelines
 - Low Disease Activity
 - Moderate to High Disease Activity
Rheumatoid Arthritis - ACR ... Tapering DMARDs - Treatment ... Guidelines #management #treatment
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
JAK-STAT pathway -> Incr ... chondrocytes -> Incr ... AKT pathway -> Incr ... strength - Incr ... endocrinology #pathophysiology