7604 results
Myocarditis 

5 Principles of
Myocarditis:
1. Build clinical suspicion
2. Decide on EMBx
3. Manage acute cardiac injury
4. Manage chronic
steroids, calcineurin inhibitor ... #Myocarditis #diagnosis ... #management #cardiology
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
• Direct renin inhibitor ... Renin release inhibition ... of aldosterone inhibition ... #differential #diagnosis
HIV Antiretroviral Pharmacokinetic Boosters - Ritonavir & Cobicistat 

Ritonavir & Cobicistat are 2 pharmacokinetic boosters used
actually a protease inhibitor ... and a 3A4 inhibitor ... is just a 3A4 inhibitor ... because of the CYP inhibition
Antiplatelet Medications - Summary Table

Aspirin - Inhibits cyclooxygenase, preventing formation of thromboxane A2
 • Acute coronary
combination with P2Y12 inhibitor ... Dipyridamole - PDE5 inhibition ... (and PDE3 inhibition ... Cilostazol - PDE3 inhibition
Heart Failure with Reduced Ejection Fraction (HFrEF) - Guideline Directed Medical Therapy - Initiation Strategies

 •
→ MRA → SGLT-2 Inhibitor ... Beta-Blocker + SGLT-2 Inhibitor ... management #GDMT #cardiology
Atrial Fibrillation (A-Fib) Summary

Symptoms:
• Palpitations, light-headedness, dizziness, dyspnea, exercise intolerance, chest pain, near-syncope, syncope.

Why?
Cardiac:
	• Valvular heart
Direct thrombin inhibitor ... Fibrillation #AFib #diagnosis ... #management #cardiology
Oral Hypoglycemics in Diabetes Management
1  INSULIN SENSITIZER
 • TZD 
     -
CARB ABSORPTION INHIBITOR ... alpha-glucosidase inhibitor ... GLP breakdown by inhibiting
Important Cardiac Transplant Medications and Side Effects
 • Cyclosporine (Sandimmune, generic) - Calcineurin inhibitor, decreasing T
- Calcineurin inhibitor ... - Calcineurin inhibitor ... , inhibiting T lymphocyte
Prothrombin Time (PT) and Partial Thromboplastin Time (PTT)

Prothrombin Time (PT) - Often Elevated in:
 • Vitamin
deficiency or inhibitor ... deficiency or inhibitor ... deficiency or inhibitor ... laboratory #hematology #diagnosis
Anticoagulant specific factor inhibition. 

#anticoagulation #clotting #INR #heparin #LMWH #NOAC #warfarin #coumadin #rivaroxaban  #Xarelto #apixaban
specific factor inhibition