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Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
• Direct renin inhibitor ... Renin release inhibition ... of aldosterone inhibition
HIV Antiretroviral Pharmacokinetic Boosters - Ritonavir & Cobicistat Ritonavir & Cobicistat are 2 pharmacokinetic boosters used
actually a protease inhibitor ... and a 3A4 inhibitor ... is just a 3A4 inhibitor ... because of the CYP inhibition
Antiplatelet Medications - Summary Table Aspirin - Inhibits cyclooxygenase, preventing formation of thromboxane A2 • Acute coronary
combination with P2Y12 inhibitor ... Dipyridamole - PDE5 inhibition ... (and PDE3 inhibition ... Cilostazol - PDE3 inhibition
NSAIDS and their effects on the Kidney - Pathophysiology Arachidonic Acid metabolites into alternative pathways that modify
Prostaglandin inhibition ... HTN, Edema • Inhibition ... KidneyDisease #nephrology
Allopurinol and its active metabolite inhibit xanthine oxidase, the enzyme that converts hypoxanthine to xanthine and
Inhibition of this ... druginformation #nephrology
Diuretics sites of action on the nephron 1) Acetazolamide (carbonic anhydrase inhibitor) 2) Osmotic diuretics (e.g. mannitol) 3) Loop
carbonic anhydrase inhibitor ... #pharmacology #nephrology
Uremic Asterixis on Physical Exam Dr. Arvind Canchi @arvindcanchi #Uremia #Asterixis #PhysicalExam #clinical #video #neurology #nephrology
#PhysicalExam #clinical ... #video #neurology ... #nephrology
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 Causes of HyperKalemia - Differential Diagnosis Increased extracellular K+: • Tissue injury • Hemolysis • Rhabdomyolysis •
Hypovolemia • RAAS inhibitor ... • Calcineurin inhibitor ... blockers - MCW Nephrology
Oral Hypoglycemics in Diabetes Management 1 INSULIN SENSITIZER • TZD -
CARB ABSORPTION INHIBITOR ... alpha-glucosidase inhibitor ... GLP breakdown by inhibiting
Important Cardiac Transplant Medications and Side Effects • Cyclosporine (Sandimmune, generic) - Calcineurin inhibitor, decreasing T
- Calcineurin inhibitor ... - Calcineurin inhibitor ... , inhibiting T lymphocyte
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