22 results
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
Liver Enzymes (LFTs ... • AST/ALT elevation ... Liver #Enzymes #LFTs ... Transaminitis #diagnosis #differential ... #hepatology
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
Function Test (LFTs ... ) Elevation AST ... Hepatocellular injury ... #FunctionTest #LFTs ... #diagnosis #hepatology
Differential Diagnosis for ST Segment Elevations
 - ACUTE STEMI 
 - PULMONARY EMBOLISM 
 - LBBB
Differential Diagnosis ... for ST Segment Elevations ... ACUTE STEMI - PULMONARY ... TRAUMATIC BRAIN INJURY ... #STEMI #Differential
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Function Tests (LFTs ... ) - Differential ... Drug-induced liver injury ... #Differential # ... Diagnosis #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs ... Bilirubin - +/- elevation ... chemistry #diagnosis #differential ... #Hepatology #transaminitis ... #LFTs #RValue #
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
- Differential ... Differential Diagnosis ... #Differential # ... Diagnosis #hepatology ... Transaminitis #LFTs
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Drug-induced Liver Injury ... dose dependent injury ... Chronic - ongoing ↑ LFTs ... Idiosyncratic #differential ... gastroenterology #hepatology
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver Injury ... Patterns #Liver #Injury ... #hepatology #LFTs ... transaminitis #differential
Hepatopulmonary Syndrome (HPS) 

HPS-differential diagnosis:
1. Pulmonary vasculature
2. Diseases of the lung parenchyma
3. Pleura and diaphragm

HPS-diagnosis:
1. Patients
(HPS) HPS-differential ... Pulmonary vasculature ... HPS-severity classification ... Syndrome #HPS #hepatology ... #pulmonary #diagnosis
Shock Classification and Differential Diagnosis
SHOCK
 • MAP <65, SBP <90, drop in SBP > 40
 •
Shock Classification ... and Differential ... Medications, Spinal Cord Injury ... , CVP > 12 • Pulmonary ... #Differential #