33 results
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... Anti-cardiolipin (aCl ... LAC) • Sjogren Syndrome ... #diagnosis #associations ... #table
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Systemic Lupus Erythematosus ... Demyelinating Syndrome ... #SLE #CNS #neurology ... #rheumatology # ... #management #treatment
Effects of Strokes by Location - Anterior vs Posterior Localization

Anterior Circulation 
 - MCA 
 -
- MCA - ACA ... Artery #Strokes #Syndromes ... Localization #Effects #Neurology ... #Diagnosis #Table ... Review in Clinical Neurology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... block • Sjogren syndrome ... #SLE #Summary #diagnosis ... #rheumatology # ... management
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
(ACLE) • Erythematous ... Differential Diagnosis ... Non-autoimmune rheumatologic ... La, anti-Jo-1, SCL ... #Diagnosis #Rheumatology
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
limb Gitelman syndrome ... tubule Liddle syndrome ... Defects #Kidney #Nephrology ... #Diagnosis #Differential ... #Table
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Systemic Lupus Erythematosus ... least 2 joints • Neurologic ... Systemic #Lupus #Erythematosus ... #diagnosis #rheumatology
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Anti-Scl-70 - Scleroderma ... La) - Sjogren's syndrome ... Goodpasture's syndrome ... Associations #diseases #diagnosis ... #table #rheumatology
ISCHEMIA Trial - Management Algorithm for patients with Stable Angina

Stress Test -> ? +moderate or severe
ISCHEMIA Trial - Management ... acute coronary syndrome ... (ACS) evaluation ... or management. ... Angina #ChestPain #Diagnosis
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
Systemic lupus erythematosus ... scleroderma) - Anti-Scl ... cases • Sjögren syndrome ... Antineutrophil #antibodies #diagnosis ... #rheumatology #