30 results
Tumor lysis syndrome (TLS) - Pathophysiology:
→ Massive tumor cell lysis
→ Release of large amounts of K+,
Tumor lysis syndrome ... (TLS) - Pathophysiology ... ALL, AML, NHL → AKI ... #TumorLysis #syndrome ... #TLS #Pathophysiology
Pathophysiology of Tumor Lysis Syndrome (TLS)
Tumor Cell Lysis
-> Release of DNA
 • Purines -> Hypoxanthine /
Pathophysiology ... of Tumor Lysis Syndrome ... (TLS) Tumor Cell ... Hypocalcemia • Hyperkalemia ... #TLS #Pathophysiology
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
of Tumor Lysis Syndrome ... Laboratory TLS ... : • AKI (defined ... hydroxide • Hyperkalemia ... #TumorLysis #Syndrome
Tumor lysis syndrome refers to the constellation of metabolic disturbances that occurs when large numbers of
Tumor lysis syndrome ... hyperuricemia, #hyperkalemia ... acutekidneyinjury #Pathophysiology ... #Presentation #TLS ... #Workup #tumorlysissyndome
HepatoRenal Syndrome - Pathophysiology

Dr. Edgar V. Lerma @edgarvlermamd - Nephrology Secrets https://amzn.to/34t5DgJ

#HRS #HepatoRenal #Syndrome #Pathophysiology #Diagnosis
HepatoRenal Syndrome ... - Pathophysiology ... #HepatoRenal #Syndrome ... #Pathophysiology ... #AKI
Workup of Hypercalcemia - Differential Diagnosis Algorithm
High or Normal PTH:
 • Hyperparathyroidism: Parathyroid adenoma, Parathyroid hyperplasia,
Workup of Hypercalcemia ... disease, Milk Alkali Syndrome ... disease, Viral Syndromes ... Diagnosis #Algorithm #Workup ... #nephrology #PTH
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
Kidney Injury (AKI ... Cancer Related • Hypercalcemia ... Capillary leak syndrome ... Kidney #Injury #AKI ... Classification #Nephrology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... fever - ACS, AKI ... : • Pathophysiology ... hydration - Hyperkalemia ... #TLS #diagnosis
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Kidney Injury - AKI ... Workup Algorithm ... Abdominal compartment syndrome ... • Cardio-renal syndrome ... #Workup #Algorithm
Causes of HyperKalemia - Differential Diagnosis
Increased extracellular K+:
 • Tissue injury
 • Hemolysis
 • Rhabdomyolysis
 •
Causes of HyperKalemia ... • Tumor lysis syndrome ... Elimination: • AKI ... blockers - MCW Nephrology ... MCW_Nephrology #HyperKalemia