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diagnosis differential causes management workup classification leukemia aplastic cll disorders elevatedmcv lymphocytic macrocytosis mds myelodysplastic syndrome thrombocytosis apml approach blood
Aplastic Anemia Summary • Definition • Pathophysiology • DDx: AA vs Hypocellular MDS • Expectation •
Aplastic Anemia ... Definition • Pathophysiology ... Expectation • Rx Algorithm ... #diagnosis #oncology ... #hematololgy
Anemia - Underproduction Diagnostic Algorithm - Iron deficiency anemia - Anemia of chronic inflammation - Anemia
Diagnostic Algorithm ... - Anemia of chronic ... of chronic kidney ... Underproduction #Algorithm ... #hematology #diagnosis
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... Differential Diagnosis Algorithm ... RA, SLE, PRV, Chronic ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Differential Diagnosis Algorithm ... Polycythemia Vera • Chronic ... : • Acute or Chronic ... Iron deficiency anemia ... #Causes #Hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Differential Diagnosis Algorithm ... of Chronic Disease ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Approach to Leukocytosis - Differential Diagnosis Algorithm Features of hematologic malignancy: • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
Differential Diagnosis Algorithm ... Features of hematologic ... hepatomegaly • Labs: anemia ... predominant immature cells ... #hematology #WBC
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... hemolysis, deficiency anemia ... Inflammatory Conditions: Rheumatologic ... • Infections: Chronic ... #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Differential Diagnosis Algorithm ... RBCs on Smear • Chronic ... • Anemia of Chronic ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Differential Diagnosis Algorithm ... Age > 50 • Chronic ... Reed-Sternberg Cells ... #Causes #Hematology ... #Oncology
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Differential Diagnosis Algorithm ... T-cell - CD7, CD3 Chronic ... Pelger-Huet, Macrocytic anemia ... or λ), Smudge Cells ... Blood #Disorders #hematology
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