29 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... in APML Epidemiology ... initiation • Differential ... #management #hematology ... #oncology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Rebound effect from treatment ... Inflammatory Conditions: Rheumatologic ... Vasculitides, IBD ... , Celiac disease ... Kawasaki, Nephrotic syndrome
Idiopathic Inflammatory Myopathies - 
Dermatomyositis (DM), Immune-Mediated Necrotizing Myopathy (IMNM), Antisynthetase Syndrome (ASS), Inclusion Body Myositis
Antisynthetase Syndrome ... Body Myositis (IBM ... Myopathy #Comparison #Managment ... #algorithm #Rheumatology ... #Differential
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Diagnosis Algorithm ... Inflammatory: • IBD ... disorders • Celiac disease ... effect following treatment ... #Causes #Hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... = funny-shaped cells ... only curative treatment ... #treatment #hematology ... #oncology
Eosinophilia - Differential Diagnosis Algorithm
Idiopathic Eosinophilia
Primary Eosinophilia:
 • Primary hypereosinophilic syndrome
 • Eosinophilic Leukemia
 • MPN/MDS
Eosinophilia - Differential ... Diagnosis Algorithm ... ), Heme malig (AML ... IBD Stanford Internal ... #Diagnosis #Algorithm
Short Stature - Differential Diagnosis Algorithm
Normal Variant, Normal Puberty Onset (BA = CA)
 • Familial Short
Short Stature - Differential ... Diagnosis Algorithm ... • Cushing's Disease ... Panhypopituitarism Treatment ... Celiac, IBD) •
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... Diagnosis and Management ... thrombocythemia), Autoimmune disease ... #treatment #hematology ... #differential
Iron Deficiency Anemia - Differential Diagnosis Algorithm

Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR

 • Blood loss:
Diagnosis Algorithm ... Gastrectomy, WHDA syndrome ... Structural: Celiac disease ... Tropical sprue, IBD ... #ferritin #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... extramedullary disease ... smear: Blasts APML ... • Tumor lysis syndrome ... #Oncology #Diagnosis